Physiology - Lads Flashcards

1
Q

List the major male reproductive hormones?

A
  • GnRH (Hypothalamus)
  • Gonadotrophins LH & FSH (Ant Pit)
  • Testosterone (Testis)
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2
Q

Sperm is produced where?

A

In the seminiferous tubules of the testes

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3
Q

What cells are found int he seminiferous tubules and what are their actions?

A
  • Germ cells (spermatogonia) produce sperm
  • Sertoli cells produce inhibin and support germ cells
  • Interstitial or Leydig cells produce testosterone
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4
Q

What does inhibin do?

A

Have a -ve feedback effect on FSH- stimulates spermatogenesis

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5
Q

So we know the Gonadotrophins are important in male reproduction, describe the action of FSH?

A

Induces spermatogenesis in the spermatogonia within the seminiferous tubules

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6
Q

So we know the Gonadotrophins are important in male reproduction, describe the action of LH?

A

Triggers Leydig cells to produce androgens resulting in:

1) Sustentactular cells within the seminiferous tubules
2) 2nd* male sex characteristics

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7
Q

Where does sperm go from the testes?

A
  • Efferent Ductules to the epididymis

- Then its carried by the Vas (ductus) deferens to meet the ducts from the seminal vesicles/prostate

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8
Q

What do the seminal vesicles/prostate produce?

A

Semen

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9
Q

Where does semen/sperm mix go after the vas deferens/Seminal vesicle duct?

A

Travels the ejaculatory duct to the urethra from which it is then ejaculated

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10
Q

Describe the process of spermatogenesis:

A

Spermatogonium underoges mitosis –> Primary Spermatocyte

1* Spermatocyte undergoes Meiosis I –> 2 2* spermatocytes

2* spermatocytes undergo meiosis II –> 4 Spermatids

Spermatids undergo Spermiogenesis to form mature sperm cells

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11
Q

Describe the lifespan of a sperm

A

takes 60-75 days to be produced

Takes 10-14 days to be transported to the epidydimis

Takes about 30 seconds to ejaculate

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12
Q

How many sperm are produced per day?

A

30million a day

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13
Q

How many sperm are in ejaculate?

A

20-100 million per ml

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14
Q

List some factors than can effect oogenesis/spermatogenesis?

A

Hormonal:

  • Genetics
  • Tumours
  • Meds
  • Functional problems

Production Site:

  • Genetic
  • Cancer treatment
  • Surgery
  • Trauma
  • Infection
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