Physiology Final Flashcards
Anatomy is study of ?; Physiology is the study of ?
Structure; Function
What is pathophysiology?
Failure of homeostasis
What are the levels of organization?
Chemical, Cellular, Tissue, Organ, Organism
Name all the life processes.
Metabolism, Responsiveness, Movement, Growth, Differentiation, Reproduction
What is homeostasis
The steadystate
What is extracellular fluid made up of
Plasma and interstitial fluid; surrounds chemical composition
What are the 2 types of homeostasis
Feedforward (made in anticipation of change) and feedback (after change is detected)
What is negative feedback?
Opposes initial change
What is positive feedback?
Amplifies initial change (ex. contractions)
Parts of negative feedback
Sensor/receptor (change detected), control center (activates the effector), effector (changes back to normal)
intrinsic vs extrinsic controls
local controls within organ vs controls outside organ (nervous and endocrine system)
Is fever good or bad
Good!!!! (negative feedback)
What chemicals make up 96% of body composition?
CHON
Parts of an atom?
nucleus, protons(+), neutrons(0) , electrons(-), electron shell
atom #?
atomic element
mass #?
P+N
atomic mass
P+N+E
isotope
same element, different #
radioactive isotope
unstable, decays over time into different element
halflife
time for half of atoms to decay into another form
ionization
ion produced by gain or loss of electrons
molecule
2 or more atoms that share electron
free radical
atom with unpaired electron in outer shell, unstable
acid
H+, one or more anions, proton donor
base
OH-, one or more cations, proton acceptor
Cation
ionic bond; + charge
Anion
ionic bond; - charge
Covalent bond
sharing of electrons
hydrogen bonds
helps cohesion
solvent vs solute
solvent dissolves solute
hydrophilic
water loving; polar
hydrophobic
water fearing; nonpolar
pH
Neutral=7; acidic= <7; basic= >7
kinetic energy
matter in motion
potential energy
energy stored by matter
enzymes/catalysts
very specific; can speed up chemical reactions by increasing frequency of collision, lowering activation energy, and orienting molecules properly (needs less activation energy)
Synthesis reaction
anabolism; A+B=AB
Decomposition reaction
catabolism; AB= A+B
Exchange reaction
AB+CD=AD+CB
Reversible reaction
AC=A+C
inorganic vs organic
lacks carbon vs always have carbon and often times hydrogen; always have covalent bonds
solution
has solute and solvent
colloid
similar to solution; larger particles can scatter light (milk)
suspension
will eventually settle out (blood)
Protein organization
primary- kind, #, amino acid order
secondary- folding into specific shape; alpha helix or beta pleated sheet
tertiary- more coiling and folding; globular proteins
quaternary- 2 or more separate poly peptide chain; hemoglobin
purine
A or G
pyrimidine
C or T (replaced by U in RNA)
isomers
same molecular formula, different structure
Layers of skin
Epidermis, dermis, hypodermis
Cells in epidermis
Keratinocytes, Melanocytes, Langerhans cells, Merkel cells
Skin pigments
Hemoglobin (red pigments in red blood cells), Melanin, Carotene (yellow/orange color)
Albinism
complete/partial absence of pigment
Vitiligo
Depigmentation patches
Skin glands
Sebaceous(oil) glands- connected to hair follicles
Eccrine Sweat glands- most numerous
Apocrine Sweat glands- hairy areas
Ceruminous glands- ear canal
Skin functions
Thermoregulation(sweat + blood flow to dermis), blood reservoir(8-10% of total blood flow), protection, cutaneous sensation(tactile, thermal, pain), excretion+ absorption, synthesis of Vitamin D
Rule of 9’s
estimates surface area of adult affected by burn
How many degrees of burns
3
Phospholipid
Head (polar, hydrophilic) (Choline,Phosphate,Glycerol); Tail (nonpolar, hydrophobic) (Fatty acid)
ion channel
integral; allows ions to pass through bilayer
transporter protein
integral; changes shape to transport specific substances across membrane
receptor
integral; recognizes specific ligand and alters cells function somehow
enzyme
integral and peripheral; catalyzes reaction in or out of cell
cell identity marker
glycoprotein; distinguishes your cell from anyone else’s (not twins). Ex is MHC proteins (major histocompatibility)