physiology Flashcards
influx of what ion causes depolarisation
sodium
efflux of what ion causes repolarisation
potassium
when a cell is depolarised what ion channels open
calcium channels - influx then a claim induced exocytosis of neurotransmitter
what is the most common neurotransmitter
glutamate
does glutamate active cation or anion receptors
cation (positively charged)
does GABA/glycine active cation or anion channels
anion (negatively charged)
does GABA/glycine cause depolarisation or hyperpolarisation
hyperpolarisation - inhibitory response
does glutamate cause depolarisation or hyper polarisation
depolarisation - excitatory response
what neurotransmitters can active inotropic ligand gated ion channels (nicotinic AcH receptor channels)
Glutamate, GABA, Glycine, ACh and Serotonin
these mediate fast neurotransmission
what neurotransmitters can activate metabotrophic G -protein coupled receptors- slow neurotransmission
all except glycine
metabrotropic receptor are muscarinic G protein receptors
what type of neurons are lower motor neurons - in terms of morphology
multipolar
what type of neurons are dorsal root ganglion/sensory neurons in terms of morphology
pseudo unipolar
what type of afferent fibres are nociceptor fibres and what lamina of rexed are they found in
laminae I and II A-delta and C fibres
what afferent fibres are in the DCML eg A, B, C
A-alpha and A-beta
what are the laminae of rexed for A-alpha and A-beta fibres respectively
A-alpha - laminae VII and IX
A-beta- laminae III and VI