Physiology Flashcards

1
Q

What effect does hypercapnia have on cerebal blood flow?

A

Cerebral vasodilation

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2
Q

What kind of pleural effusion does heart failure cause?

A

Transudate (low protein)

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3
Q

State Boyle’s Law

A

At a constant temperature, the pressure exerted by a gas varies inversely with the volume of a gas

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4
Q

What is the Law of LaPlace?

What’s more likely to collapse smaller or larger alveoli?

A

P=2T/r

- smaller radius alveoli = higher tendency to collapse

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5
Q

State Dalton’s law

A

The total pressure of a mixture of gases = SUM of partial pressures of each component gas

Adding Daltons = ADd

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6
Q

Alveoli who are well ventilated but not adequately prefused are known as?

A

Alveolar dead space

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7
Q

What factor most increase pulmonary ventilation?

A

Tidal volume (more so than resp rate - depth of breath is more important)

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8
Q

Describe the neuron pathways involved in normal/forceful expiration and normal inspiration?

What ones are passive and which ones are active processes?

Where are these neurons found?

A

Normal inspiration

  • active
  • firing of DORSAL neurons

Normal expiration

  • passive
  • GAPS in firing of dorsal neurons

Forceful expiration

  • active
  • firing of VENTRAL neurons

Medulla

Vexed = angry/ forced expiration breathing = V = ventral

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9
Q

What chemoreceptors detect arterial oxygen partial pressure. When stimulated, they cause hyperventilation and increased cardiac output?

Where are they found?

A

Peripheral chemoreceptors

Carotid and aortic bodies

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10
Q

What chemoreceptors are found in the brainstem. They respond to CSF [H+]

Where are they found?

A

Central in the medulla

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11
Q

What chemoreceptors, when stimulated, can compensate for metabolic acidosis by triggering increased elimination of CO2?

A

Peripheral chemoreceptors

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12
Q

What effect does the Bohr effect has on O2 haemoglobin graph?

What 4 things cause the Bohr effect?

What shape is the oxygen haemoglobin vs myoglobin graph?

A

Right shift - increased oxygen dissocation

Increase [H+]
Increase CO2
Increase 2.3 BPG
Increase temp

Sigmodial- haemoglobin
Hyperbolic - myoglobin

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13
Q

How many haem groups does haemoglobin have vs. myoglobin?

A

4 - haem

1 - myo

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