physiology Flashcards

1
Q

internal respiration

A

intracellular mechanisms which consumes oxygen to produce carbon dioxide

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2
Q

external respiration

A

ventilation
exchange in lungs
transport
exchange in tissues

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3
Q

Boyles law

A

at any constant temperature the pressure exerted by a gas varies inversely with the volume of the gas. as the volume of a gas increases the pressure exerted by the gas decreases

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4
Q

forced vital capacity

A

maximum volume of air that can be forcibly expelled from lungs following a maximum inspiration

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5
Q

forced expiratory volume in one second

A

volume of air that can be expired the first second of FVC

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6
Q

FEV1/FVC

A

more than 70%

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7
Q

obstructive lung disease

A

lower FEV1

low FEV1/FVC

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8
Q

restrictive lung disease

A

lower FVC and FEV1

normal FEV1/FVC

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9
Q

dynamic airway compression

A

is the rising pleural pressure during active expiration compresses the alveoli and airways
makes active expiration more difficult in patients with airway obstruction

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10
Q

pulmonary compliance

A

measure of effort put into stretching or distending the lungs

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11
Q

pulmonary ventilation

A

tidal volume x respiratory rate

volume of air breathed in and out per minute

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12
Q

alveolar ventilation

A

(tidal volume - dead space) x respiratory rate

volume of air exchange between atmosphere and alveolar per minute

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13
Q

ventilation perfusion

A

mismatch is resolved by smooth muscle action of airways and arterioles

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14
Q

alveolar dead space

A

ventilated alveoli that are not perfused

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15
Q

rate of gas exchange is influenced by

A

partial pressure gradient of oxygen and carbon dioxide
diffusion coefficient for oxygen and carbon dioxide
surface area if alveolar membrane
thickness of alveolar membrane

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16
Q

Dalton’s law of partial pressures

A

the total pressure exerted by gaseous mixture is the sum of the partial pressures of each component

17
Q

Fick’s law of diffusion

A

amount of gas that moves across a sheet of tissue in unit time is proportional to the area of the sheet and inversely proportional to its thickness

18
Q

Henry’s law

A

amount of a given gas dissolve in a given type and volume of liquid at a constant temperature proportional to the partial pressure of the gas in equilibrium with the liquid

19
Q

oxygen delivery index

A

oxygen content of arterial blood x cardiac index

20
Q

means of carbon dioxide transport

A

solution 10%
bicarbonate 60%
carbamino compounds 30%

21
Q

Haldane effect

A

is removing oxygen from Hb increases the ability of Hb to pick up CO2 and CO2 generated H+, workes with the Bohr effect

22
Q

Bohr effect

A

the oxygen dissociation curve is shifted right due to conditions in the tissues, meaning more oxygen is released

23
Q

where is breathing controlled

A

medulla

24
Q

dorsal firing

A

results in inspiration - active

25
Q

gaps in dorsal firing

A

results in expiration - passive

26
Q

increased dorsal firing

A

activates ventral firing causing forceful expiration - active

27
Q

PC in pons

A

stimulation terminates inspiration

is stimulated when dorsal fire, regulates rhythm

28
Q

apneustic centre

A

excites inspiratory medulla