Physiology Flashcards
diastole
ventricular relaxation and blood filling
stroke volume
volume of blood ejected from each ventricle during systole
isovolumetric
contraction but no change in volume
4 stages of cardiac cycle?
- Isovolumetric ventricular contraction
- ventricular ejection/emptying
- isovolumetric ventricular relaxation
- ventricular filling
Mean arterial pressure definition and equation
average arterial BP over entire cardiac cycle
MAP = CO x TPR
Heart sounds
‘LUBB DUBB”
1st - closure of AV valve
2nd - closure of SL valve
Atrial kick
At end of diastole. Elevated atrial pressure forces small amount of blood into ventricle
When are peak ventricular and aortic pressure reached?
before the end of ventricular ejection
Does the ventricle empty fully?
No
Stroke volume = EDV - ESV
Cardiac output equation
CO = SV x HR
cardiac muscle SA node
The nervous system increases the stroke volume by increasing which 3 things?
End-diastolic volume
Plasma epinephrine
Activity of sympathetic nerves to the hear
HR is increased by what?
increase in plasma epinephrine
stimulation of sympathetic nerves to the heart
inhibition of PS nerves to the heart
How does sympathetic stimulation increase HR?
increases slope of pacemaker potential by:
- increasing the F-type channel permeability
- more Na+ enters the cell
- faster depolarisation
Where is epinephrine produced?
adrenal medulla
what does PS stimulation do?
decreases the rate of spread of excitation through the atria and AV node