Physiology Flashcards
What is soft tissue growth measured by?
Weight
What is bone growth measured by?
Height
What plays a permissive role in bone and soft tissue growth?
IGF, GH and Thyroid hormone
How does insulin support bone and soft tissue growth?
Provides glucose energy
What does bone growth require from the diet?
Calcium ad protein
What attaches to the collagen lattice in the ECF?
Hydroxyapatite - calcium phosphate crystals
What is the most common calcium phosphate?
Hydroxyapatite
What is compact/cortical bone?
Outer layer - provides strength
What is trabecular bone?
Inner layer; open, cell-filled spaces between struts of calcified lattice
What are osteoblasts?
Modified fibroblasts that are specialised bone-forming cells
What do osteoblasts produce?
Osteoid
What binds to osteoid?
Hydroxyapatite
What is osteoid?
Collagen and protein mixture
What do osteocalcin and osteonectin do?
Aid in bone deposition
What is the site of linear growth of long bones?
Epiphyseal plate