Bone and Joint Infections Flashcards
1
Q
What are the 2 different classifications of osteomyelitis?
A
Haematogenous
Non-haematogenous
2
Q
What are the 2 different classifications of non-haematogenous osteomyelitis?
A
Direct inoculation - trauma, surgery, etc.
Local invasion - pressure ulcer, sinus disease, etc.
3
Q
How does haematogenous osteomyelitis develop?
A
Bacteria colonise the venous sinuses in the looped capillaries going through the metaphysis.
4
Q
Why are bacteria able to colonise venous sinuses in metaphyses?
A
Slow flow through looped capillaries in venous sinuses
Venus sinusoids are protected from immune response due to poorly developed RE system and poor penetration of WBCs
Leads to abscess formation
5
Q
What will colonisation of venous sinuses eventually lead to?
A
Abscess formation in metaphysis
