Physiology 1.2 Flashcards

1
Q

Describe the main anatomical features of the airways and the gross anatomical features of the lung.

A

The main anatomical features of the airways and the gross anatomical features of the lung can be observed with the naked eye.

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2
Q

Identify the different classes of airways and the two different types of alveolar cells.

A

There are different classes of airways and two types of alveolar cells within the respiratory system.

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3
Q

Explain why and how resistance to air flow varies across the respiratory tract.

A

Resistance to air flow varies across the respiratory tract, and it is important to understand the reasons behind this variation.

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4
Q

Describe the functions of the nose in the respiratory system.

A

The nose plays a crucial role in warming, moistening, and filtering the air we breathe, making it more comfortable for inhalation.

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5
Q

Discuss the role of the pharynx in the respiratory system.

A

The pharynx, also known as the throat, serves as a common conduit shared with the digestive system and plays a key role in the respiratory tract.

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6
Q

Explain the significance of breathing through the nose versus the mouth.

A

Breathing through the nose is more comfortable as it effectively warms, moistens, and filters the air, while breathing through the mouth is less comfortable due to its inefficiency in these functions.

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7
Q

Describe the structure and function of the ciliated epithelium in the nose.

A

The ciliated epithelium in the nose is responsible for trapping mucus and aiding in the removal of particles from the respiratory system.

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8
Q

Discuss the relationship between the nose’s surface area to volume ratio and its function in the respiratory system.

A

The nose’s large surface area to volume ratio is essential for its effectiveness in warming and moistening the inhaled air.

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9
Q

Explain the connection between the pharynx and the larynx in the respiratory system.

A

The pharynx connects the back of the nose and mouth to the larynx, which is a critical part of the respiratory system.

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10
Q

Describe the function of the epiglottis in the respiratory system.

A

The epiglottis acts as a gate to the respiratory system, closing when swallowing to prevent food or liquid from entering the lungs.

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11
Q

What is the role of the larynx in speech production?

A

The larynx houses the vocal cords and allows us to change the tension in them, controlling the way air travels across them to produce speech sounds.

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12
Q

Define the trachea and its location in the body.

A

The trachea is the main airway of the respiratory system, located below the larynx and running down to the sternal angle at the top of the sternum.

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13
Q

How do the bronchi divide in the respiratory system?

A

The trachea splits underneath the sternal angle to give the two primary bronchi, one going to each lung, which then continue to divide about 24 times into smaller airways.

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14
Q

Describe the structure and function of the alveoli in the lungs.

A

The alveoli are microscopic air sacs where gas exchange occurs, allowing for the exchange of oxygen and carbon dioxide, forming the functional level of the lungs.

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15
Q

What is the boundary between the upper and lower respiratory tract?

A

The larynx serves as the boundary, with everything above it belonging to the upper respiratory tract and everything below it belonging to the lower respiratory tract.

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16
Q

Describe the significance of theaveric image of respiratory system shown in the content.

A

The cadaveric image displays real lungs a deceased individual, providing a rare opportunity for students to observe the anatomy.

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17
Q

What is the role of the diaphragm in respiration?

A

The diaphragm is a crucial muscle for inspiration, allowing air to enter the lungs.

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18
Q

Define the pleural cavity and its importance.

A

The pleural cavity is a space inside the thoracic cavity that becomes significant in understanding lung inflation and deflation.

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19
Q

How are the lobes of the lungs distributed?

A

The right lung has three lobes (superior, middle, and inferior) separated by two fissures, while the left lung has two lobes (superior and inferior) separated by one fissure.

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20
Q

Describe the appearance of the lungs in the cadaveric image.

A

The lungs appear dark, possibly indicating smoking or exposure to pollution, and exhibit a larger pleural cavity due to deflation after death.

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21
Q

What separates the thoracic cavity from the abdominal cavity?

A

The diaphragm, a sheet of muscle, separates the thoracic cavity from the abdominal cavity.

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22
Q

Do the lungs in the cadaveric image fill the entire thoracic cavity in life?

A

Yes, in life, the lungs would fill the entire thoracic cavity, but after death and deflation, they separate from the chest wall, enlarging the pleural cavity.

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23
Q

Describe the difference in lobe distribution between the right and left lungs.

A

The right lung has three lobes and two fissures, while the left lung has two lobes and one fissure, with some space occupied by the heart.

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24
Q

What is the fibrous pericardium, and where is it located?

A

The fibrous pericardium is a fibrous tissue surrounding the heart and is located underneath the chest wall, above the heart.

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25
Q

Describe the thoracic cavity.

A

The thoracic cavity is defined by the ribs, with the inferior border being the diaphragm, and it contains the pleural cavity that surrounds the lungs.

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26
Q

What is the function of the pleural cavity?

A

The pleural cavity is important for the mechanics of breathing and allows air to move in and out of the lungs.

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27
Q

Define primary bronchi.

A

The trachea branches at the level of the sternal angle to give us the left and right primary bronchi, with one primary bronchus going to each lung.

28
Q

How are the lungs further divided beyond lobes?

A

The lung tissue is further split into segments, with one tertiary bronchi going to each segment of the lung.

29
Q

Describe the structure of the airways beyond the bronchi.

A

Beyond the bronchi, the airways continue to branch, eventually losing cartilaginous rings and becoming bronchioles, which terminate in alveoli.

30
Q

What is the function of alveoli in the respiratory system?

A

Alveoli are tiny, blind-ended sacs filled with air where gas exchange takes place, as their walls are thin enough for oxygen and carbon dioxide to be exchanged.

31
Q

Describe the process of creating resin cast of a of lungs.

A

Pumping the lungs full of resin, allowing it to, and then dissolving the lung tissue with acid to obtain a cast of the respiratory tree.

32
Q

What is the difference between the right and left primary bronchi?

A

The right primary bronchi is slightly wider and has a more vertical trajectory compared to the left primary bronchi.

33
Q

How does the diameter of the airways change as we move down the respiratory tree?

A

The diameter of the airways gets smaller as we move down the respiratory tree, with the trachea having the largest diameter and the smallest bronchioles having the smallest diameter.

34
Q

Define broncho-pulmonary segments.

A

They are the segments of the lung supplied by tertiary bronchi.

35
Q

Do the laws of physics regarding resistance to airflow apply to the respiratory system?

A

No, the greatest amount of resistance to airflow occurs in the largest airways, contrary to what physics would predict based on vessel diameter.

36
Q

Describe the cross-sectional area of the trachea compared to the bronchioles.

A

The cross-sectional area of the trachea is about 2.5 centimeters squared, while the cross-sectional area of the bronchioles is about five thousand centimeters squared, making the total area available for airflow much greater in the smaller airways.

37
Q

How does the number of air particles in the airways change as we move up the respiratory tree?

A

As we move up the respiratory tree, more and more air particles are jostling for a proportionally smaller part of the airway.

38
Q

What is the significance of the difference in diameter and cross-sectional area between the trachea and bronchioles?

A

The difference in diameter and cross-sectional area explains why the greatest amount of resistance to airflow occurs in the largest airways, despite the laws of physics predicting otherwise based on vessel diameter.

39
Q

Describe the relationship between airway diameter and resistance in the system.

A

As airway diameter increases in the respiratory system, the increase in diameter is not proportional to the number of air molecules trying to move through it, resulting in an increase in resistance.

40
Q

Define dead space in the context of the respiratory system.

A

Dead space in the respiratory system refers to the conducting zone, where upper airways have walls too thick for gas exchange to occur, resulting in air that cannot participate in gas exchange.

41
Q

How does the resistance to airflow vary in the respiratory system?

A

The resistance to airflow is greatest in the upper airways and trachea, and lowest in the lower airways, with the ability to be dynamically altered by changing the diameter of the airways.

42
Q

Describe the role of bronchial smooth muscle in altering airway diameter and resistance in the respiratory system.

A

Bronchial smooth muscle can contract to decrease airway diameter and increase resistance to airflow, or relax to increase airway diameter and decrease resistance.

43
Q

How does the sympathetic nervous system impact bronchial smooth muscles in the respiratory system?

A

The sympathetic nervous system can act on bronchial smooth muscles to cause contraction, leading to a decrease in airway diameter and an increase in resistance to airflow.

44
Q

Describe the role of the nervous system on beta two receptors in the lungs.

A

The sympathetic nervous system acts on beta two receptors in the lungs, causing bronchial smooth muscle relaxation, increasing the diameter of airways, and reducing resistance to airflow.

45
Q

What is the function of adrenaline or noradrenaline binding to beta two receptors in the lungs?

A

Adrenaline or noradrenaline binding to beta two receptors in the lungs brings about relaxation of the bronchial smooth muscle, increasing the diameter of airways and reducing resistance to airflow.

46
Q

Define the relationship between the sympathetic nervous system and the fight-flight response in relation to the respiratory system.

A

The sympathetic nervous system triggers the fight-flight response, leading to bronchial smooth muscle relaxation, increased airway diameter, and reduced resistance to airflow, facilitating increased ventilation and oxygen delivery to the muscles.

47
Q

Describe the structure and function of the bronchiole smooth muscle in the respiratory system.

A

The bronchiole smooth muscle can contract or relax, changing the diameter of the bronchiole and therefore the resistance to airflow, ultimately affecting gas exchange in the alveoli.

48
Q

How does gas exchange occur in the respiratory system and the cardiovascular system?

A

Gas exchange occurs in the alveoli of the respiratory system, in direct contact with the capillary network of the cardiovascular system, allowing for the exchange of oxygen and carbon dioxide.

49
Q

Describe the role of elastic fibers in the alveoli during inspiration and expiration.

A

Elastic fibers in the alveoli allow for inflation during inspiration and store energy, which is released during expiration to force air out of the respiratory system. This process is essential for normal physiological function.

50
Q

What is the function of the pulmonary artery in the gas exchange process?

A

The pulmonary artery carries deoxygenated blood full of carbon dioxide from the right side of the heart to the lungs, where gas exchange occurs in the capillary beds, allowing for the exchange of carbon dioxide and oxygen.

51
Q

Define the relationship between the alveoli and the capillary network in the respiratory and cardiovascular systems.

A

The alveoli are surrounded by a dense capillary network, allowing for direct contact between the respiratory and cardiovascular systems, facilitating gas exchange between the alveoli and the blood vessels.

52
Q

Describe the process of expiration in the respiratory system.

A

Expiration at rest is passive, as the energy stored in the elastic fibers of the alveoli during inspiration is released to squeeze the alveoli and force air out of the respiratory system, without the use of additional energy.

53
Q

Describe the process of expiration at rest.

A

Expiration at rest is passive, involving the cessation of contraction in the muscles involved in inspiration and the release of energy stored in elastic fibers during inspiration.

54
Q

Define the role of type one alveolar cells in gas exchange.

A

Type one alveolar cells make up the bulk of the alveolar wall and are responsible for facilitating gas exchange due to their thin walls.

55
Q

How do type two alveolar cells contribute to respiratory function?

A

Type two alveolar cells secrete surfactant, which makes the work of breathing easier and aids in inspiration.

56
Q

Describe the relationship between type one cells and capillaries in the respiratory system.

A

Type one cells are directly abutted to capillaries, as they are the sites where efficient gas exchange takes place.

57
Q

What is the function of elastic fibers in the respiratory system?

A

Elastic fibers allow the alveoli to inflate during inspiration and squeeze during expiration to push air out of the respiratory system.

58
Q

Do macrophages play a role in the respiratory system?

A

Yes, macrophages are important for immune function in the respiratory system, helping to protect against infections entering the body through the respiratory route.

59
Q

Describe the structure of the alveoli.

A

The alveoli are small air sacs in the lungs responsible for gas exchange. They have an enormous surface area, about 80 square meters, and are extremely thin to facilitate gas exchange.

60
Q

Define anatomical dead space in the respiratory system.

A

Anatomical dead space refers to the air in the trachea and bronchi, which does not participate in gas exchange due to the thick walls of the airways.

61
Q

How does airway resistance affect lung function?

A

Airway resistance determines how much air flows into the lungs at any given pressure difference between the atmosphere and the alveoli. It is a major determinant of lung function.

62
Q

Describe the impact of diseases like emphysema on the respiratory system.

A

Diseases like emphysema result in a destruction of the alveoli, leading to a loss of surface area available for gas exchange. This has a massive impact on respiratory function.

63
Q

Do the walls of the upper airways allow for gas exchange?

A

No, the walls of the upper airways are too thick to allow gases to cross, and their function is purely the conduction of air to and from the alveoli.

64
Q

What is the function of the conducting zone in the respiratory system?

A

The conducting zone consists of the trachea, bronchi, and bronchioles, and it is responsible for conducting air to and from the alveoli.

65
Q

Describe the size and capacity of the lungs.

A

Each lung has a capacity of about three liters, totaling to a lung capacity of about six liters. The surface area of the alveoli, about 80 square meters, fits into this volume due to its thinness.

66
Q

How does the surface area of the alveoli contribute to gas exchange?

A

The large surface area of the alveoli, about 80 square meters, is hugely significant in terms of gas exchange. Gases can only exchange over the very thin membranes found in the type one alveolar cells.