physiological organisation + control III Flashcards

1
Q

how are bilatarian nervous systems organised

A

two neurones with paired ganglia. they are joined by connectives longitudinally and commissures laterally

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2
Q

how do leeches move

A

they have 5 locomotion behaviours. their sensory input is controlled by touch (6), pressure (4) and noxious (4) receptors

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3
Q

how do leeches achieve bending behaviour

A

antagonistic contraction eg when there is dorsal stimulation the dorsal side will contract and the ventral will relax to bend away from the stimulus. small relay to neighbouring segments allows for a smooth bend

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4
Q

how do leeches achieve shortening behaviour

A

when an end of the leech is touched it retracts. this is due to receptors innervating L2 neurones which cause the longitudinal muscle to contract. touch receptors also innervate C2 neurones which facilitates intersegment flow via S cells

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5
Q

describe habituation

A

reaction to a stimulus diminishes with repeated exposure to the same stimulus

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6
Q

describe sensitisation

A

increased response when a new stimulus is applied simultaneously with the original repeated stimulus

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7
Q

what is 5 HT

A

serotonin, a neuromodulator. it delays habituation and increases S cell excitation for more intersegment flow

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8
Q

what is a central pattern generator CPG

A

a collection of inter neurones which oscillate in activity for rhythmic behaviours such as swimming and breathing

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9
Q

how are CPGs altered

A

higher control centres or neuromodulators can alter the frequency or phase of the oscillations

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10
Q

how is swimming behaviour initiated in leeches

A

it is episodic, not continuous, and is stimulated eg by touch or waves which could indicate a predator or prey

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11
Q

how are touch/ wave stimuli detected in leeches

A

they are detected by sensillar movement receptors which are tiny hairs. signals from them are transduced to initiate a cascade

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12
Q

how does the cascade cause swimming in leeches

A

it is initiated by SMRs and cause CPGs to initiate oscillation where longitudinal and flattener waves contract out of phase to propel the body forward

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13
Q

what are pacemakers

A

an alternative to CPGs. they are controlled by cAMP, Ca2+ and negative feedback

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14
Q

why are Aplysia a model organism

A

their cells are large and easily identifiable. they also have a simple nervous system affected by neuromodulation and memory

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15
Q

what is the gill withdrawal reflex

A

the gills withdraw when siphon is touches as a defence mechanism. it undergoes habituation due to decreased levels of glutamate unless sensitisation occurs

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16
Q

what is short term sensitisation

A

a single tail shock with the siphon touch which produces a limited response

17
Q

what is long term sensitisation

A

a sequence of tail shocks with siphon touches to produce a much greater and longer lasting response

18
Q

what is the mechanism of short term sensitisation

A

5HT promotes glutamate release and also activates cAMP which increases Ca2+ influx

19
Q

what is the mechanism of long term sensitisation

A

cAMP recruits MAPK and CREB1 which promote genes for new synaptic connections, increasing the strength of synaptic signals and therefore producing a larger response