Physiological Changes of Aging Flashcards
Changes in cardiovascular circulation
- Decrease contractibility, increase fat and collagen
- myocardial hypertrophy (esp. left ventricle)
- decrease cardiac reserve
- thickening and fibrosis of heart valves
What happens in cardiovascular circulation?
- decrease cardiac output
- decrease blood flow to vital organs and periphery
-Incomplete closure of valves, therefore heart murmurs - Baroreceptors in the aortic arch & carotid sinus become less sensitive
- Arterial blood vessels thicken, becoming more rigid and loosing elasticity
-Blood supply to various organs decreases & peripheral resistance increases. Rigid arteries contribute to CAD, HTN & PVD - Lower extremity edema develops, risk for DVTs
Changes in cardiovascular electricity
- Cellular aging and fibrosis, changes the conduction system
- There is a ↓ number of pacemaker cells in SA node (by 75, only 10% of normal # of pacemaker cells)
What happens in cardiovascular electricity?
-There is a ↓ in amplitude of the QRS complex & lengthening of the PR, QRS & QT intervals
(these are defined as cardiac arrhythmias = atrial fibrillation, atrial flutter, etc.)
-Sinus bradycardia, premature beats
Sinus Bradycardia
Rate ˂ 60 Regularity regular rhythm P wave normal, upright, uniform PR interval 0.12 – 0.20 seconds QRS 0.06 – 0.10 seconds T wave normal
Atrial Fibrillation
Rate atrial rate 350–450, vent rate varies with AV conduction
Regularity irregularly irregular
P wave no P waves, replaced by fine fibrillatory waves
PR interval indiscernible
QRS 0.06 – 0.10 seconds
T wave indiscernible
Structural changes in respiratory system
- ↑ anteroposterior diameter of the thoracic cage
- ↓ elastic recoil of the lung and ↓ chest wall compliance
- Alveolar ducts and bronchioles enlarge and the number of alveoli decreases
What happens in structural changes of respiratory system
- Barrel chest appearance, displacement of apical pulse
- ↓ vital capacity, ↑ residual volume; therefore diminished breath sounds particularly at lung bases
- Reduced overall efficiency of ventilatory exchange, therefore a decrease in PaO2
Changes in respiratory defenses
- A decline in cell-mediated immunity and formation n of antibodies (↓ in alveolar macrophages)
- ↓ cough force and less functional cilia
What happens in changes in respiratory defenses
- ↑ risk of respiratory infections
- ↓ cough effectiveness and ↓ secretion clearance
Changes in respiratory control
- ↓PaO2
- ↑PaCO2
What happens in changes of respiratory control
- ↓ response to hypoxemia
- ↓ response to hypercapnia
- Ability to maintain acid-base balance ↓
- In addition, retained secretions, excessive sedation, or positioning that impairs chest expansion may substantially alter PaO2 or SpO2 values
Changes in muscle, ligaments, and tendons
- Muscle fibers decrease and have atrophy of muscle cells
- Loss of elasticity and ↓ flexibility in ligament/tendons
- Gradual reduction in the speed and power of skeletal or -voluntary muscle contractions
What happens in changes in muscle, ligaments, and tendons
- ↓ muscle mass, tone & strength
- Movement is more rigid, changes in gait and ↓ in agility
- Slowed reaction time and reflexes
Changes in joints
- Deterioration of joint cartilage
- Loss of water from disk between vertebrae, therefore narrowing of intervertebral spaces
What happens in changes in joints
- Osteoarthritis; pain & joint stiffness, ↓ ROM, and crepitation on movement
- Loss of height from disk compression
Changes in bones
- ↓ in bone density
- Decalcification of bones
- Osteoporosis
- Posture and structural changes (deformities such as dowager’s hump)
Changes in mouth
- Loss of teeth
- ↓ taste buds, ↓ sense of smell
- ↓ salivary production
- Atrophy of gingival tissue
What happens in changes of mouth
- Difficulty chewing may lead to decrease in appetite
- Diminished sense of taste (esp. with salty & sweet) may leads to excessive use
- Diminished sense of taste & smell may result in ↓ appetite and weight loss
- Dry oral mucosa
- Poor-fitting dentures
Changes in esophagus or stomach
- ↓ tone & motility of the esophagus
- Lower esophageal sphincter pressure is decrease (or becomes incompetent)
- ↓ gastric acid secretion, atrophy of gastric mucosa and less resistant to damage
What happens in changes in esophagus or stomach
- ↓ esophageal peristalsis, therefore propulsion of food is less effective, complaints of dysphagia & heartburn (GERD)
- Entry of food is delayed into the stomach, causing a premature feeling of fullness
- Food intolerance
Changes in small intestine
- ↓ motility and ↓ secretions of digestive enzymes in the small intestines
- Liver - ↓ hepatic blood flow, ↓ in actual size, and ↓ in production of enzymes
- Pancreas - ↑ fibrosis, decreased secretion of enzymes and hormones
What happens in changes in small intestines
- Slowed intestinal transit, delayed absorption
- Impaired drug metabolism
- Impaired fat absorption and decreased glucose intolerance
Changes of the bottom of the barrel or your ass
- ↓ anal sphincter tone and nerve supply to rectal area
- ↓ muscle tone, ↓ motility in large intestines
- ↑ transit time
What happens in changes of your ass
- Fecal incontinence
- Flatulence, abdominal distension
- Constipation, fecal impaction
Changes in kidneys
- ↓ number of nephrons, ↓ function of loop of Henle and tubules
- ↓ renal blood flow, ↓ glomerular filtration rate
What happens in changes of the kidneys
- A reduced ability to concentrate urine and conserve water (potential for hydration is increased)
- ↓ creatinine clearance – excretion of toxins/drugs is decreased, ↑ BUN level
Changes in urinary bladder
- ↓ elasticity and muscle tone of bladder, weakening of urinary sphincter
- ↓ ability of bladder to completely empty
- ↑ residual urine
What happens in changes of the urinary bladder
- Stress incontinence, frequency, urgency
- Nocturia
- Retention
Changes in male reproductive system
- ↓ testosterone levels
- Prostate enlarges
- Testes atrophy
- ↓ sperm count
- ↓ rate & force of ejaculation
- ↑ refractory period after orgasm
Changes in female reproductive system
- ↓ estrogen levels
- Ovaries, uterus, cervix slowly atrophy
- ↓ in vaginal secretions
- Vaginal pH becomes alkaline
- Cessation of menses
- ↑ refractory period after orgasm