Physiological And Pathological Formation of The Brain And Spinal Cord Flashcards

1
Q

What does ectoderm form

A

Skin, nervous system

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2
Q

What does endoderm form

A

Epithelial lining of gut, respiratory system, liver and pancreas

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3
Q

What does mesoderm form

A

Notochord, muscular system

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4
Q

What week is gastrulation

A

3rd

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5
Q

What do migrations neural crest cels form

A
Sensory dorsal root ganglia of spinal cord and CN 5 7 9 10
Schwann cell 
Adrenal medulla 
Bony skull
Meninges
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6
Q

When should neural tube close

A

4th embryonic week

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7
Q

Incidence of spina bifida

A

1/1000

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8
Q

Env factors affecting spina bifida

A

Folic acid

Maternal diabetes

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9
Q

Meckel syndrome

A

Cystic kidney malformation

Extra fingers

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10
Q

Learning disability IQ

A

Less than 70

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11
Q

CSF mls

A

120 mls

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12
Q

CSF function

A

Cushions brain and helps metabolites

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13
Q

CSF circulation

A

Through subarachnoid spaces through ventricles

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14
Q

Where is csf produced

A

Choroid plexus

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15
Q

Where is csf absorber

A

Arachnoid granulation in superior sagittal sinus

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16
Q

Hydrocephalus

A

Accumulated CSF
Increased cranial press

Can cause macrocephaly in kids

Obstructive- tumour / haemorrhage
Non obstructive- increased csf production