PhysioLec: NMJ Flashcards

1
Q

TRUE OR FALSE: Serotonin is formed by the hydroxylation & decarboxylation of Tryptophan and is present in blood platelets, GI tract & brainstem.

A

True

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2
Q

TRUE OR FALSE: Decrease in Ca++ presynaptically explains
habituation.

A

True

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3
Q

TRUE OR FALSE: Kainate receptors are metabotropic receptors.

A

False

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4
Q

TRUE OR FALSE: Histamine comes from Histidine.

A

True

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5
Q

TRUE OR FALSE: Long-term memory can be explained by long-term potentiation.

A

True

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6
Q

TRUE OR FALSE: The NMJ of smooth muscles have junctional folds.

A

False

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7
Q

TRUE OR FALSE: ACh is formed from the combination of choline & acetate

A

False

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8
Q

TRUE OR FALSE: The NMJ of skeletal muscles contain only one
neurotransmitter.

A

True

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9
Q

TRUE OR FALSE: Mechanical response in muscle starts prior to the electrical response.

A

False

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10
Q

TRUE OR FALSE: Norepinephrine comes from the amino acid Phenylalanine.

A

False

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11
Q

TRUE OR FALSE: Studying in a room with closed window blinds can lead to habituation.

A

True

The stimulus is benign so the response of the post-synaptic cell will be decreased.

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12
Q

TRUE OR FALSE: Having more specific receptors for a neurotransmitter makes them more selective to the transmitter.

A

True

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13
Q

TRUE OR FALSE: Histamine is released by mast cells (heparin-containing cells) and is also released by the posterior hypothalamus.

A

True

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14
Q

TRUE OR FALSE: Neurons that uses epinephrine as a neurotransmitter are called epinephergic neurons.

A

False

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15
Q

TRUE OR FALSE: GABA B receptors are metabotoropic receptors that act via G – protein to increase K+ conductance. Potassium exits the postsynaptic cell and inhibits it

A

True

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16
Q

TRUE OR FALSE: The partial, non-propagated potential at the NMJ of skeletal muscle is called an EPSP

A

False

17
Q

TRUE OR FALSE: Post-synaptic accumulation of Ca++ explains
long-term potentiation.

A

True

18
Q

TRUE OR FALSE: Epinephrine has more affinity to the α receptors.

A

False

19
Q

TRUE OR FALSE: End-plate potentials always produce a propagated action potential in skeletal muscles.

A

True

20
Q

TRUE OR FALSE: To inhibit a skeletal muscle, inhibitory end-plate
potentials will be generated at the NMJ

A

False

21
Q

TRUE OR FALSE: GABA A receptors are ionotropic receptors and act at Cl- channels. Chloride enters and hyperpolarizes the cell
which inhibits the post synaptic cell.

A

True

22
Q

TRUE OR FALSE: Feeling tired and sleepy at the end of the day,
the neurotransmitter secreted is Serotonin.

A

True

23
Q

TRUE OR FALSE: Glycine is excitatory in the brain but inhibitory in the spinal cord. It acts by an increase in Cl- conductance

A

True

24
Q

TRUE OR FALSE: The NMJ of smooth and cardiac muscles have
varicosities.

A

True

25
Q

TRUE OR FALSE: Stimulating the AMPA & kainate receptors can
‘kick off’ the Mg++ block of the NMDA.

A

True

26
Q

TRUE OR FALSE: Aspartate is one of the major inhibitory
neurotransmitters in the brain.

A

False

27
Q

They have the inability to maintain contraction.
A. EATON LAMBERT SYNDROME
B. MYASTHENIA GRAVIS
C. NONE

A

B. MYASTHENIA GRAVIS

28
Q

They are weak at first then become near normal strength.
A. EATON LAMBERT SYNDROME
B. MYASTHENIA GRAVIS
C. NONE

A

A. EATON LAMBERT SYNDROME

29
Q

Antibodies against presynaptic ACh vesicles
A. EATON LAMBERT SYNDROME
B. MYASTHENIA GRAVIS
C. NONE

A

C. NONE

30
Q

Antibodies against presynaptic voltage-gated Ca++ channels.
A. EATON LAMBERT SYNDROME
B. MYASTHENIA GRAVIS
C. NONE

A

A. EATON LAMBERT SYNDROME

31
Q

Antibodies against ACh nicotinic receptors.
A. EATON LAMBERT SYNDROME
B. MYASTHENIA GRAVIS
C. NONE

A

B. MYASTHENIA GRAVIS