Physio Lab Final Flashcards
Explain the function of the skeletal muscle and how it is innervated.
- Contractions aid in the circulation of blood through blood vessels
- Innervated by the Somatic Nervous System (SNS)
Explain the function of the cardiac muscle and how it is innervated.
- Specific to the heart
- Helps with pressure circulation around body
- Innervated by the Autonomic Nervous System (ANS)
Explain the function of the smooth muscle and how it is innervated.
- Moves food, urine, and reproductive tract secretions
- Located in hollow organs
- Innervated by the Autonomic Nervous System (ANS)
Which muscle has intercalated discs?
Cardiac muscle
How many nuclei does each muscle have?
Cardiac: 1-2
Smooth: 1
Skeletal: Many
Which muscles are striated vs. nonstriated?
Striated: Cardiac , Skeletal
Nonstriated: Smooth
Which muscles are voluntary vs involuntary?
Voluntary: Skeletal
Involuntary: Cardiac, Smooth
T/F: all muscles above need calcium ions for contraction
True
Epimysium (Outer)
Connective tissue that surrounds a muscle
Perimysium (Middle)
Connective tissue surrounding a muscle fascicle
Endomysium (Inner)
Connective tissue that surrounds a muscle fiber
Muscle Fascicles
A bundle of muscle fibers
Muscle Fibers
Composed of many smaller fibers called Myofibrils
Myofibrils
Contains Myofilaments (Thick and Thin filaments) arranged in repeating functional units known as Sarcomeres
SarcolEMMa
the cell MEMbrane
SarcoPLASM
the cytoPLASM
Sarcoplasmic Reticulum
Storage site for calcium ions
Triad
the T-tubule and its flanking terminal cisternae
What are thick filaments composed of? Do they move?
- Composed of elongated proteins called myosin
- THEY DO NOT MOVE! THINK THICC DOES NOT EXERCISE/MOVE
What do thick filaments contain?
Actin binding site
ATP binding site
What do thin filaments consist of? Do they move?
- Consist of actin, troponin and tropomyosin
- YES THEY MOVE! THINK THIN PPL ARE THIN BECAUSE THEY EXERCISE/MOVE
How do you remember actin?
ACTIN HAS ACTIVE (BINDING) SITES
Tropomyosin
Actin-binding protein which regulates muscle contraction by blocking the formation of a crossbridge between thick and thin filaments
Troponin
Attached to tropomyosin; regulates the tropomyosin-troponin complex
How do you remember the types of troponin?
Troponin C: binds to Calcium
Troponin I: binds to Inhibitors
Troponin T: binds to Tropomyosin
Explain the different parts of the sacromere.
- Z disc: limits of the sarcomere
- M line: middle of the sarcomere
- H band: contains thick filaments only
- I band: contains thin filaments only
- A band: contains both thick and thin filaments
What is the site of communication between a somatic motor neuron and a muscle cell?
Neuromuscular Junction
What would happen if drug/poison blocked ACh
receptors?
No electrical impulse or contraction because ACh would not bind
What would happen if calcium channels on the terminal
cisternae were blocked?
No contraction because calcium would not be released
According to the sliding filament theory, what is responsible for muscle contraction?
Crossbridge formation
How do you undo muscle contraction?
Must break the crossbridge formation which happens when an ATP molecule binds and detaches the myosin head from the actin site
What is the role of acetylcholinesterase (AChE) in the neuromuscular junction?
Breaks down ACh
How would a low AChE enzyme level impact muscular contraction?
The less ACh that is broken down, the more ACh present
What solutions had the most prominent, slight, and no contractions in the glycerinated muscle with ATP expirement?
- 0.2% ATP + KCl + MgCl2 had the most prominent
- 0.2% ATP + Distilled water had a slight contraction
- KCl + MgCl2 had no contraction
The buildup of ____ ___ leads to the burning sensation during exercise.
Lactic acid
How is ATP generated?
Via cellular respiration
How does glucose turn into lactic acid?
Glucose -> Pyruvate -> Lactic acid
VIA LACTIC ACID FERMENTATION
T/F: the right lung has 3 lobes and the left lung has 2 lobes
true