Physical Activity Flashcards
1
Q
What is meant by sarcopenia?
A
Loss of skeletal muscle mass and strengthen due to ageing.
2
Q
State 3 factors associated with sarcopenia.
A
Changes in anabolic hormones e.g. reduced GH/IGF, testosterone. Metabolic dysregulation - increases reactive O2 species. Inflammation - increases degradation. Anabolic resistance to feeding and exercise - reduces protein synthesis. Reduced regeneration from exercise induced damage - compromised satellite cell behaviour.