phys 5

Question 1

means of CO2 transport in the blood

Answer 1

“in solution i.e. dissolved CO2 (10%)
as bicarbonate (60%)
As Carbamino compounds (30%)
“

Question 2

“bicarbonate is formation is catalysed by

where is this enzyme found”

Answer 2

“carbonic anhydrase

found in red blood cells”

Question 3

carboamino compounds are formed by

Answer 3

combination of CO2 with terminal amine groups in blood proteins

Question 4

the boher effect

Answer 4

tbc…

Question 5

the haldane effect

Answer 5

“Removal of O2 from Hb increases
the ability of Hb to pick-up CO2 and
CO2 generated H+
“

Question 6

“The Boher effect and the haldane effect work in

synchrony to facilitate”

Answer 6

“O2 liberation and uptake of CO2 & CO2 generated H+ at tissues
“

Question 7

chloride shift

Answer 7

“exchange of bicarbonate(HCO3-) ions and chloride(Cl-) ions across the membrane of red blood cells

Loss of bicarbonate ions from RBC causes positive charge inside RBC which is balanced by diffusion of chloride (Cl-) ion from plasma into the RBC.”

Question 8

what does the boher effect do to O2-Hb dissociation curve and what effect does this have

Answer 8

The Bohr Effect Shifts the O2-Hb Dissociation Curve to the Right and this facilitates the Removal of O2 from Haemoglobin at Tissue Level

Question 9

Hb binding to O2 occurs where and how this binding affect O2

Answer 9

“occurs at the lungs

weakens its ability to bind to CO2 and H+”

Question 10

effect of oxygen on the CO2 dissociation curve

Answer 10

shifts to the right - The Haldane effect

Question 11

Reduced Hb can bind more ___ than ___

Answer 11

CO2, HbO2