phys 3 Flashcards

1
Q

anatomical dead space

A

inspired air which remains in the airways where it is not available for gas exchange

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2
Q

pulmonary ventilation(L) =

A

“tidal volume (L/breath) x Respiratory Rate (breath/min)

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3
Q

Alveolar Ventilation is less than pulmonary ventilation because of

A

the presence of anatomical dead space

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4
Q

alveolar ventilation =

A

(tidal volume – dead space volume) x Respiratory Rate

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5
Q

pulmonary ventilation is the

A

volume of air breathed in and out per minute

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6
Q

Alveolar Ventilation is

A

the volume of air exchanged between the atmosphere and alveoli per minute

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7
Q

why is alveolar ventilation more important than pulmonary ventilation

A

alveolar ventilation represents new air available for gas exchange with blood

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8
Q

what can be done to increase pulmonary ventilation

A

“the depth of breathing(tidal volume) and

rate of breathing (RR) increase”

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9
Q

the transfer of gases between the body and atmosphere depends upon

A

“ventilation

perfusion”

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10
Q

ventilation is the rate at which

A

gas is passing through the lungs

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11
Q

blood flow and ventilation vary from ____ to ____ of the lung

A

“bottom, top

they are both higher at the bottom”

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12
Q

why are some ventilated alveoli considered as alveolar dead space

A

they are not adequately perfused with blood

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13
Q

physiological dead space =

A

the anatomical dead space + the alveolar dead space

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14
Q

Local controls act on the smooth muscles of ____ and ____ to match ____ to ____

A

airways, arterioles, airflow, blood flow

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15
Q

Increase in alveolar O2 concentration as a result of increased ventilation causes

A

pulmonary vasodilation which increases blood flow to match larger airflow

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16
Q

what happens in areas in which perfusion is greater than ventilation

A

“CO2 increases in the area
O2 decreases in the area

dilation of local airways
constriction of local blood vessels

airflow increases
blood flow decreases”

17
Q

effect of decreased O2 on pulmonary arterioles and systemic arterioles, respectively

A

vasoconstiction, vasodilation

18
Q

effect of increased O2 on pulmonary arterioles and systemic arterioles, respectively

A

vasodilation, vasoconstriction

19
Q

factors that influence the rate of gas exchange across alveolar membrane

A

“partial pressure gradient of O2 and CO2
diffusion coefficient for O2 and CO2
surface area of alveolar membrane
thickness of alveolar membrane”

20
Q

partial pressure of a gas determines

A

the pressure gradient for that gas

21
Q

The partial pressure of gas (1) in a mixture of gases that don’t react with each other is

A

The pressure that gas (1) would exert if it occupied the total volume for the mixture in the absence of other components

22
Q

Ptotal =

A

P1 + P2 +…+ Pn

23
Q

partial pressure of a gas is

A

The pressure that one gas in a mixture of gases would exert if it were the only gas present in the whole volume occupied by the mixture at a given temperature.

24
Q

value of the total atmospheric pressure

A

101Kpa

25
Q

value of water vapour pressure in the lungs

A

about 47mmHg

26
Q

why is there a water vapour pressure

A

air in the respiratory tract is saturated with water

27
Q

alveolar gas equation

A

PAO2 = PiO2 - [PaCO2/0.8]

28
Q

“Respiratory Exchange Ratio (RER)

A

“RER is the ratio of CO2 produced/O2 consumed)

normal value Is 0.8 for someone eating a mixed diet.”

29
Q

where do gases move due to the partial pressure gradient

A

from higher to lower partial pressures

30
Q

diffusion coefficient

A

the solubility of gas in membranes

31
Q

what does a big gradient between PAO2 and PaO2 indicate

A

problems with gas exchange in the lungs or a right to left shunt in the heart

32
Q

ficks law of diffusion

A
"The amount of gas  that moves 
across a sheet of tissue in unit 
time is proportional to the area of 
the sheet but inversely proportional
 to its thickness"
33
Q

features of the lungs that help facilitate effective gas exchange

A

“large surface area

thin membranes”