PHS 201: Muscle Physiology Flashcards

1
Q

What are the types of muscle tissue?

A
  1. Skeletal -Skeletal muscle is the type that attaches to our bones and is used for movement and maintaining posture
  2. Cardiac - It is only found in the heart and it pumps blood
  3. Smooth - found in organs of the body such as the G.I. tract. Smooth muscle in the G.I. tract moves food and its digested products
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2
Q

Characteristics of cardiac muscle

A

Branching cells
one or two nuclei per cell
striated
involuntary
medium speed contractions (not as fast as skeletal but faster than that of smooth muscle)

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3
Q

Smooth muscle characteristics

A

Fusiform cells
One nucleus per cell
Nonstriated
Involuntary
Slow wave-like contractions
Found in the walls of hollow organs

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4
Q

Skeletal muscle characteristics

A

Long cylindrical cells
many nuclei per cell
striated
involuntary
rapid contractions

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5
Q

Function of skeletal muscle

A

Produce movement
maintain posture and body position support soft tissues
guard entrance or exit
maintain body temperature
store nutrients reserves

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6
Q

What forms the tendon or aponeurosis of muscles

A

Endomysium perimysium and epimysium come together at ends of muscles to form connective tissue attachment to burn matrix i.e. tendon or aponeurosis

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7
Q

Role of the skeletal muscle muscular system

A

Supplies large amounts of oxygen supplies nutrients
carries away waste

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8
Q

Describe skeletal muscle fibers

A

They are very long
develop through fusion of mesodermal cells (myoblasts)
become very large
contain hundreds of nuclei

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9
Q

Nerve supply of skeletal muscle

A

Somatic nerves

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10
Q

Nerve supply of cardiac muscle

A

Autonomic nerves

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11
Q

Nerve supply of smooth muscle

A

Autonomic nerve fibers

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12
Q

Smooth muscle is also known as

A

Visceral muscle

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13
Q

What is fasciculi

A

The various groups in which muscle fibers are arranged in the connective tissue sheath that covers each fasciculus is called perimysium

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14
Q

What’s connected tissue sheath is directly beneath the facia of muscle

A

Epimysium

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15
Q

What is an Aponeurosis

A

Thin flat and stretched tough muscle tendon

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16
Q

What is sarcolemma

A

Plasma membrane that encloses each muscle fiber that lies beneath the Endomysium

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17
Q

Function of the endomysium

A

Each muscle fibers covered by a connective tissue layer called the Endomysium

18
Q

What is the cytoplasm of the muscle

A

Sarcoplasm

19
Q

Structures embedded within the sarcoplasm

A

Nuclei
Myofibril
Gogi apparatus
mitochondria
sarcoplasmic reticulum
ribosomes glycogen droplets occasional lipid droplets

20
Q

What are Cohnheim’s areas or fields

A

These are groups in which some Myofibrils are arranged in

21
Q

What is a sarcomere

A

The sarcomere is defined as the structural and functional unit of a skeletal muscle.
An arrangement of overlapping contractile proteins, actin and myosin within a myofibril to form light and dark striations.

22
Q

Describe the skeletal muscle levels of organization

A
  1. A muscle is made of many muscle cells, called muscle fibers
    1.1 bundles of muscle fibers are arranged in fascicles
  2. A muscle fiber is packed full of long fiber-like contractile organelles called myofibrils
  3. Myofibrils are made up of contractile proteins- myosin and actin
  4. Myosin and actin are arranged in overlapping stripes, organized into a unit called the sarcomere
23
Q

What is myosin?

A

Thick filament of within a myofibril

24
Q

What is actin?

A

Thin filament within a myofibril

25
Z line
Boundary of sarcomere where actin attaches to adjoining sarcomere the centers of the I bands at two ends of the sarcomere
26
A band
Dark band Stretches end to end of myosin, contains both actin and myosin filaments
26
A band
Dark band Stretches end to end of myosin, contains both actin and myosin filaments
27
I band
Light band Space between myosin (only contains actin)
28
H zone
Non-overlapping regions of myosin only (no actin)
29
M line
Centre of the sarcomere holding adjacent myosin together with supporting proteins
30
What is titin?
Titin: Strands of protein reach from the tips of thick filaments to the Z line, they stabilize the filaments
31
Function of sarcomere
Transverse tubules encircle the sarcomere near zones of overlap Ca2+ released by SR causes thin and thick filaments to interact Muscle contraction
32
What are the thin filament (actin) proteins?
Troponin tropomyosin F-actin Nebulin
33
Function of Tropomyosin
Is a double strand Prevents actin-myosin interaction (binds to actin hindering the biding of myosin)
34
Function of Troponin
A globular protein Binds tropomyosin to G-actin Controlled by Ca2+ (moves tropomyosin out of the way)
34
Function of Troponin
A globular protein Binds tropomyosin to G-actin Controlled by Ca2+ (moves tropomyosin out of the way)
35
Function of F-actin
F-actin (Filamentous actin) Is two twisted rows of globular G-actin The active sites on G-actin strands bind to myosin
36
Function of nebulin
Nebulin Holds F-actin strands together
37
Function of the epimysium
Dense fibrous irregular connective tissue surrounding the skeletal muscle
38
Function of the perimysium
Dense fibrous irregular connective tissue covering the fascicles
39
How does the sarcomere change during contraction?
H zone - smaller I band - smaller Z lines - closer together A band and M band, do not change
40
Describe the steps of muscle contraction
1. Muscle fibers experience a nerve impluse stimulating an action potential 2,The Ca ions bind to the troponin This binding weakens troponin-tropomoysin complex and actin Troponin moiecule changes position, rolling the tropomyosin away from the active sites on actin Thus allowing them to interact with energized myosin heads