Phenylephrine Nasal Spray 0.5%

Question 1

Class?

Answer 1

Topical vasoconstrictor.

Question 2

Mechanism of Action?

Answer 2

Stimualtes a receptors in the blood vessels of the nasal mucosa which causes their constriction and thereby decreases the risk of nasal bleeding.

Question 3

Indications and Field Use?

Answer 3

Facilitation of nasotracheal intubation.

Question 4

Contraindications?

Answer 4

Known allergy to medication.

Question 5

Adverse Reactions?

Rare with single dose, rarely absorbed systemically from nasal instillation

Answer 5

CV: Hypertension, palpitations
CNS: Tremors

Question 6

Incompatibilities/Drug Interactions?

Answer 6

None

Question 7

Adult Dosage?

Answer 7

2-4 sprays in each nostril before attempting tube insertion.

Question 8

Pediatric Dosage?

Answer 8

None.

Question 9

Routes of Administration?

Answer 9

Mucosal; spray in each nostril.

Question 10

Onset of Action?

Answer 10

Seconds

Question 11

Peak Effects?

Answer 11

30 minutes

Question 12

Duration of Action?

Answer 12

30 minutes to 4 hours

Question 13

AZ Drug Box Minimum Supply?

Answer 13

Optional: 1 bottle

Question 14

Special Notes?

Answer 14

• Single Patient Use Only
• Air or strong light causes potency loss; do not use solution if brown in color or precipitate is in bottle.
• Nasal intubation tips: examine nares for most patent side; administer topical vasoconstrictor, use ETT 0.5-1.0 mm smaller than for oral intubation; lubricate nostril and tube; tube bevel face nasal septum to avoid abrading Kiesselbach’s Plexus; advance tube along nasal floor of more patent side.