Phenylephrine Nasal Spray 0.5% Flashcards
Class?
Topical vasoconstrictor.
Mechanism of Action?
Stimualtes a receptors in the blood vessels of the nasal mucosa which causes their constriction and thereby decreases the risk of nasal bleeding.
Indications and Field Use?
Facilitation of nasotracheal intubation.
Contraindications?
Known allergy to medication.
Adverse Reactions?
Rare with single dose, rarely absorbed systemically from nasal instillation
CV: Hypertension, palpitations
CNS: Tremors
Incompatibilities/Drug Interactions?
None
Adult Dosage?
2-4 sprays in each nostril before attempting tube insertion.
Pediatric Dosage?
None.
Routes of Administration?
Mucosal; spray in each nostril.
Onset of Action?
Seconds
Peak Effects?
30 minutes
Duration of Action?
30 minutes to 4 hours
AZ Drug Box Minimum Supply?
Optional: 1 bottle
Special Notes?
- Single Patient Use Only
- Air or strong light causes potency loss; do not use solution if brown in color or precipitate is in bottle.
- Nasal intubation tips: examine nares for most patent side; administer topical vasoconstrictor, use ETT 0.5-1.0 mm smaller than for oral intubation; lubricate nostril and tube; tube bevel face nasal septum to avoid abrading Kiesselbach’s Plexus; advance tube along nasal floor of more patent side.