Aspirin, Acetylsalicylic Acid, ASA Flashcards
1
Q
Class?
A
Analgesic; antipyretic; anti-inflammatory
2
Q
Mechanism of action?
A
Blocks thromboxane A2, a potent platelet aggregate and vasoconstrictor. Decreased platelet aggregation.
3
Q
Indications and Field Use?
A
Chest pain and signs/symptoms of acute myocardial infarction.
4
Q
Contraindications?
A
- Bleeding ulcer, hemorrhagic states, hemophilia.
- Known hypersensitivity to salicylates or other non-steroidal anti-inflammatories that has led to hypotension and/or bronchospasm.
- Children and adolescents.
5
Q
Adverse Reactions?
A
- Patients with a history of asthma. Anaphylactic reactions in sensitive pts have occurred; skin eruptions.
- Other side effects rare with single dose.
6
Q
Adult dosage?
A
Cardiac:
160-324 mg (2-4 81 mg tabs), chew and swallow
7
Q
Pediatric dosage?
A
Not recommended for prehospital use in children.
8
Q
Routes of administration?
A
Oral
9
Q
Onset of Action?
A
20-30 minutes
10
Q
Peak effects?
A
2 hours
11
Q
Duration of Action?
A
4-6 hours
12
Q
Minimum Drug Box Supply?
A
324 mg
13
Q
Special Notes
A
ASA is heat and light sensitive. The odor of acetic acid (vinegar-like smell) indicated degradation of product.
