Phenotypic Detection of Bacterial Drug Resistance (M) Flashcards
What is the meaning of AMR?
Antimicrobial resistance
What is AMR?
It is a global health and development threat
What does AMR requires?
It requires urgent multisectoral action in order to achieve the Sustainable Development Goals (SDGs)
True or False
AMR is one of the top 10 global public health threats facing humanity
True, it is declared by WHO
What are the main drivers (or causes) of the development of drug-resistant pathogens?
1) Misuse and 2) overuse of antimicrobials
What are the factors that promotes the spread of microbes (whereas some of w/c can be resistant to antimicrobial treatment)?
1) Lack of clean H2O and sanitation
2) Inadequate prevention and control
Is the cost of AMR to the economy significant? Why or why not?
Yes, because in addition to death and disability, prolonged illness results in longer hospital stays, the need for more expensive medicines and financial challenges for those impacted
What is the cause of increased risk of the success of modern medicine in treating infections, including during major surgery and cancer chemotherapy?
W/out effective antimicrobials
Is phenotypic detection vital in the microbio lab? How?
Yes, because it helps clinicians prescribe appropriate antibiotics for pts especially those w/ life-threatening infections
A failure to address the problem of antibiotic resistance could result in what?
1) 10M deaths by 2050
2) Costing £66 trillion
When are penicillins discovered?
1928
When is resistance against penicillins identified?
1940
When are tetracyclines discovered?
1948
When is resistance against tetracyclines identified?
1953
When are macrolides discovered?
1948
When is resistance against macrolides discovered?
1985