Phase 4 set 3 Flashcards
what anatomical point corresponds with the base of the appendix and lies two thirds of the distance between the naval and right anterior superior iliac spine?
McBurney’s point
what might a positive Rovsing’s sign indicate
Appendicitis
what sign is it when there is right lower abdominal pain when palpating on the left lower abdomen ?
Rovsings sign
what would you likely find on a FBC in a person with appendicitis ?
neutrophil predominant leucocytosis
At what age is peak incidence of ALL?
1-4 years
what are some secondary causes of erythrocytosis?
COPD, sleep apnoea
What mutation is associated with polcythaemia vera?
JAK2 mutation
how would the Hb be abnormal in a person with polycythemia vera?
elevated Hb
What would you expect EPO levels to be like in someone with polycythaemia vera?
low
what is first line treatment for CML?
imatinib
what would bone marrow biopsy show in CML?
granulocytes at different stages of maturation
What is richter’s transformation +
sudden transformation of CML into a high grade lymphoma
what do we give to reduce the risk of thrombotic events in a person with polycythemia?
aspirin
what type of leukaemia can polycytaemia vera progress to?
Acute myeloid leukaemia
what disease is a result of reduced absorption/ overproduction of endolymph?
Meniere’s
