Pharmocology Flashcards
1
Q
What is affinity
A
How strongly a medication binds to a receptor
2
Q
What is potency
A
Amount of a medication needed to elicit an effect
3
Q
Give the 3 stages of a new drug development
A
- discovery phase
- preclinical phase
- clinical phase
4
Q
What is dose
A
Precise amount of active ingredient
5
Q
What is pharmacokinetics
A
Movement and modification of the medication in the body (what the body does to the medication)
ADME Absorption Distribution Metabolism Excretion
6
Q
What is pharmacodynamics
A
What the medication does to the body
E.g boosting the production of a certain type of protein or slowing down DNA replication
7
Q
Give 3 types of cell surface receptors
A
- Ligand-gated ion channels
- G protein coupled receptors (7 pass transmembrane receptors)
- enzyme couple receptor