Pharmarcology drug interactions Flashcards by Audrey Le Bihan | Brainscape

Q

Cisplatin (drug interaction)

A

NSAIDs

Increased nephrotoxicity

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Q

Methotrexate (drug interaction)

A

NSAIDs

Reduced excretion, increased toxicity

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Q

Cyclophosphamide (drug interaction)

A

Warfarin

Enhanced anticoagulant effect

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Q

Tamoxifen (drug interaction)

A

SSRIs (e.g., Fluoxetine)

Reduced tamoxifen effectiveness

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Q

Imatinib (drug interaction)

A

Paracetamol

Increased risk of liver toxicity

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Q

5-Fluorouracil (5-FU) (drug interaction)

A

Allopurinol

Increased 5-FU toxicity

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Q

Vincristine (drug interaction)

A

Phenytoin

Reduced phenytoin levels

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Q

Rituximab (drug interaction)

A

Live vaccines

Risk of severe infections

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Q

Etoposide (drug interaction)

A

Warfarin

Increased risk of bleeding

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Q

Capecitabine (drug interaction)

A

Warfarin

Increased anticoagulant effect

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Q

Bevacizumab (drug interaction)

A

Aspirin

Increased risk of bleeding

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Q

Erlotinib (drug interaction)

A

Omeprazole

Reduced efficacy of erlotinib

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Q

Pembrolizumab (drug interaction)

A

Corticosteroids

Reduced immune response

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Q

Trastuzumab (drug interaction)

A

Anthracyclines

Increased risk of heart failure

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Q

Carboplatin (drug interaction)

A

Aminoglycosides

Increased risk of nephrotoxicity

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Q

Lapatinib (drug interaction)

A

Proton pump inhibitors

Reduced absorption of lapatinib

Q

Lenalidomide (drug interaction)

A

Digoxin

Increased digoxin levels

Q

Irinotecan (drug interaction)

A

St. John’s Wort

Reduced irinotecan effectiveness