Pharmacology - Pneumonics and Facts Flashcards

1
Q

Drugs that act on microtubules

A

Microtubules Get Constructed Very Poorly

Mebendazole (anti-helminthic)
Griseofulvin (anti-fungal)
Colchicine (anti-gout)
Vincristine/Vinblastine (anti-cancer)
Paclitaxel (anti-cancer)
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2
Q

What is the mechanism of Ouabain?

A

Inhibits Na+/K+ ATPase by binding to K+ site

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3
Q

What is the mechanism of cardiac glycosides (digoxin and digitoxin)

A

Inhibit the Na+/K+ ATPase –> indirect inhibition of Na+/Ca2+ exchange –> increase in intracellular calcium –> increase cardiac contractility

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