Pharmacology: Overview of Analgesic drugs + their MOA Flashcards

1
Q

Difference between opium, opiate, opioid?

A
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2
Q

Site of action of COX + NSAIDs

A
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3
Q

Name analogues of morphine

A
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4
Q

Name synthetic analogues

A
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5
Q

What are 3 types of GPCRs

  • Where are they?
  • What are the analgesic effects of each GPCR?
A
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6
Q

CNS pharmacodynamics of opioids

A
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7
Q

Peripheral pharmacodynamics of opioids

A
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8
Q

Name each endogenous peptide

A
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9
Q

Effects of NSAIDs

A
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10
Q

Name a drug _____ anti-inflammatory

  • Strongly
  • Moderately
  • Minimally
A
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11
Q

NSAID mechanism of action

A
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12
Q

When is PGE2 produced?

A
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13
Q

What do PGs enhance?

A
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14
Q

% ADRs NSAIDs responsible of?

  • 1st + 2nd common ADRs
A
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15
Q

NICE/WHO pain ladder

A
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16
Q

TRPV1 receptors

A
17
Q

Capsaicin

A
18
Q

Name analgesics with multiple actions

A
19
Q

Tramadol

A
20
Q

Tapentadol

A
21
Q

α2-adrenoceptor agonists

A
22
Q

Treatment for neuropathic pain

A
23
Q

Tricyclic antidepressants

A
24
Q

Antiepileptic drugs

A
25
Q

Acupuncture

A