Pharmacology: Overview of Analgesic drugs + their MOA Flashcards
1
Q
Difference between opium, opiate, opioid?
A
2
Q
Site of action of COX + NSAIDs
A
3
Q
Name analogues of morphine
A
4
Q
Name synthetic analogues
A
5
Q
What are 3 types of GPCRs
- Where are they?
- What are the analgesic effects of each GPCR?
A
6
Q
CNS pharmacodynamics of opioids
A
7
Q
Peripheral pharmacodynamics of opioids
A
8
Q
Name each endogenous peptide
A
9
Q
Effects of NSAIDs
A
10
Q
Name a drug _____ anti-inflammatory
- Strongly
- Moderately
- Minimally
A
11
Q
NSAID mechanism of action
A
12
Q
When is PGE2 produced?
A
13
Q
What do PGs enhance?
A
14
Q
% ADRs NSAIDs responsible of?
- 1st + 2nd common ADRs
A
15
Q
NICE/WHO pain ladder
A
16
Q
TRPV1 receptors
A
17
Q
Capsaicin
A
18
Q
Name analgesics with multiple actions
A
19
Q
Tramadol
A
20
Q
Tapentadol
A
21
Q
α2-adrenoceptor agonists
A
22
Q
Treatment for neuropathic pain
A
23
Q
Tricyclic antidepressants
A
24
Q
Antiepileptic drugs
A
25
Acupuncture
