Pharmacology overdoses Flashcards
Treatment for acetaminophen overdose
N-acetylcysteine (replenishes glutathione)
Treatment for cholinesterase inhibitor poisoning/organophosphates
Atropine (competitive inhibitor) followed by pralidoxime (regenerates AChE if given early)
Treatment for amphetamine overdose
NH4Cl (acidify urine)
Treatment for antimuscarinic or anticholinergic overdose
Physostigmine salicylate and control hyperthermia
Treatment for benzodiazepine overdose
Flumazenil
Treatment for B-blocker overdose
Glucagon
Treatment for carbon monoxide poisoning
100% O2 or hyperbaric O2
Treatment for copper, arsenic, or gold overdose
Penicillamine
Treatment for cyanide poisoning
Nitrite + thiosulfate, hydroxocobalamin
Treatment for digitalis overdose
Anti-dig Fab fragments (FA2013 has normalize K+, Lidocaine, Anti-dig Fab fragments, Mg2+ - KLAM)
Treatment for heparin overdose
Protamine sulfate
Treatment for iron overdose
deFEroxamine, deFErasirox.
Treatment for lead overdose
EDTA, dimercaprol, succimer, penicillamine
Treatment for mercury, arsenic, or gold overdose
Dimercaprol (BAL), succimer
Treatment for methanol, ethylene glycol (antifreeze)
Fomepizole > ethanol, dialysis