Pharmacology overdoses Flashcards

1
Q

Treatment for acetaminophen overdose

A

N-acetylcysteine (replenishes glutathione)

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2
Q

Treatment for cholinesterase inhibitor poisoning/organophosphates

A

Atropine (competitive inhibitor) followed by pralidoxime (regenerates AChE if given early)

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3
Q

Treatment for amphetamine overdose

A

NH4Cl (acidify urine)

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4
Q

Treatment for antimuscarinic or anticholinergic overdose

A

Physostigmine salicylate and control hyperthermia

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5
Q

Treatment for benzodiazepine overdose

A

Flumazenil

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6
Q

Treatment for B-blocker overdose

A

Glucagon

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7
Q

Treatment for carbon monoxide poisoning

A

100% O2 or hyperbaric O2

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8
Q

Treatment for copper, arsenic, or gold overdose

A

Penicillamine

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9
Q

Treatment for cyanide poisoning

A

Nitrite + thiosulfate, hydroxocobalamin

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10
Q

Treatment for digitalis overdose

A

Anti-dig Fab fragments (FA2013 has normalize K+, Lidocaine, Anti-dig Fab fragments, Mg2+ - KLAM)

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11
Q

Treatment for heparin overdose

A

Protamine sulfate

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12
Q

Treatment for iron overdose

A

deFEroxamine, deFErasirox.

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13
Q

Treatment for lead overdose

A

EDTA, dimercaprol, succimer, penicillamine

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14
Q

Treatment for mercury, arsenic, or gold overdose

A

Dimercaprol (BAL), succimer

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15
Q

Treatment for methanol, ethylene glycol (antifreeze)

A

Fomepizole > ethanol, dialysis

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16
Q

Treatment for methemoglobinemia

A

Methylene blue, vitamin C

17
Q

Treatment for opioid overdose

A

Naloxone

18
Q

Treatment for salicylate overdose

A

NaHCO3 (alkalinize urine), dialysis

19
Q

Treatment for TCA overdose

A

NaHCO3 (plasma alkalinization)

20
Q

Treatment for tPA, streptokinase, or urokinase overdose

A

Aminocaproic acid

21
Q

Treatment for warfarin overdose

A

Vitamin K, plasma (if active bleeding)