Pharmacology exam #4 - Study guide Flashcards
comprehensive part/ Endocrine/ oncology drugs and immunosuppressive drugs
Cadaveric Transplantation
a dead person’s health organ transplanted to another individual in need of the organ (life-share_
Immune reconstitution inflammation Syndrome
a syndrome related to a disease-or pathogen-specific inflammatory response in patients with antiretroviral therapy being initiated or changed.
Induction Therapy
Treatment that provides these immunosuppression with drugs designed to diminish antigen presentation and T-cell response.
Living-donor transplantation
a living person organ donated to someone in need of the organ
Opportunistic Infection
Infections that occur in immunocompromised individuals who have a low white blood cell count.
Postexposure prophylaxis
the treatment regimen instituted after exposure to the HIV (human immunodeficiency virus).
Transplant rejection
this occurs when the immune system of the transplant recipient attacks the transplanted organ.
viral Load
a measurement of the amount of a virus circulating in the blood
Window Period
the time delay from infection to a positive test result
Alkylating Drug
these are killers for all phases of the cancer cell cycle. example is cyclophosphamide
Antimetabolites
this chemotherapy can cross the blood brain barrier one of the contraindications is pregnant patients and narrow therapeutic index
Antineoplastic drugs
an agent that destroys all cancer cells
Antitumor antibiotics
these are highly protein bound and can be cardiotoxic these are colored red.
Apoptosis
cell death
Biologic response modifiers
these enhance, direct, and restore the body’s immune system
Capillary-leak syndrome
rare disorder that is from extravasation of plasma proteins and fluids in the extravascular space appearance of severe hypotension/ multiorgan dysfunction.
Cell cycle-nonspecific
medications that can act during any part of the cell cycle.
Cell-cycle specific
only work during a specific part of the cell cycle.
Colony-stimulating factors
help creates red blood cells and white blood cells
Combination Chemotherapy
the combination of 2 or more chemotherapy drugs to treat cancer in patients
Cytostatic therapy
inhibits extra cell growth of cancer cells.
cytotoxic therapy
this treatment kills the cancer cells
Erythropoietin
creates red blood cells also called EPO
Hormone agonists/antagonists
these are not meant to be chemotherapy but they mask the cancer cells and use prevention to producing hormones
Metastasis
cancer spread by the blood or through the tumor to other areas of the body
Mitosis
this is a cell division
Monoclonal antibodies
antibodies made by one clone of cells or a cell line
Efavirenz
Class of medication/purpose:
Antiretroviral treats HIV-1 or HIV-2
Side effects: rash, nausea, diarrhea, CNS effects, amnesia, dizziness, impaired concentration
Adverse reactions: allergic reaction, convulsion, liver failure, neuropathy, abnormal vision, hyperlipidemia
Education: the feeling of being drunk or stoned should clear up within a few weeks
Tenofovir
Class of medication/purpose of drug: antiretroviral treats HIV-1 and Hepatits B
SE: N/V/D, Insomnia, depression, fever, chest pain
AE: Latic acidosis, hepatomegaly, renal insuficiency,
teaching: teach about safe sex practices, inform patients to avoid otc certain medications, Inform this is not a cure it treats the symptoms only and lower the amount of virus transmissible to another recipient.
Zidovudine
Medication class/purpose of drug: Antiretroviral therapy used to trat HIV infection and prevention of maternal-fetal HIV transmission
SE: Headache, malaise, Nausea, anorexia, vomiting, asthenia
AE:severe anemia, lactic acidosis, neutropenia, pancytopenia, sezures, CHF, myelosuppression
Teaching: safe practices of sex and do not drive until you are adjusted on this medication as it can cause fainting or dizziness,
Atazanavir
Medication class/ purpose of drug: antiretroviral therapy
SE: Rash, Nausea, vomiting, diarrhea, cough, fever
AE: atrioventricular block, hyperglycemia, Jaundice, lipodystrophy
Teaching: safe sex practices/
Cyclosporine
Medication Class/ Medication purpose: immunosuppressant these are used to prevent transplant rejection.
SE: Hypertension, hirsutism, infection, headache,
AE: transplant rejection, hypertension,
Teachings: do not go into large crowded areas as this drug puts you at a greater risk of infection, wear a mask when you go outside to prevent contracting a infection, drink bottled water only no tap water