Pharmacology - Ch. 21 Flashcards
Analgesics
Drugs that relieve pain without causing a loss of consciousness.
Anaphylaxis
Condition of shock caused by hypersensitivity to a drug or other substance that results in life threatening respiratory distress and vascular collapse.
Anemia
Subnormal concentration of erythrocytes or hemoglobin in the blood.
Anesthetics
Agents that reversible depress neuronal function, producing loss of ability to feel pain and/or other sensations.
Angina pectoris
Severe constricting pain in the chest, often radiating to the shoulder and down the arm, caused by ischemia (obstruction of blood supply) of heart muscle, usually result of coronary disease.
Antagonist
Substance that tends to nullify the action of another drug.
Anticholinergics
Drugs that block the passage of impulses through the parasympathetic nerves.
Arrhythmia
Variation from the normal rhythm of heartbeat.
Atherosclerosis
Condition in which thickening of the wall of a blood vessel occurs because of the deposition of plaque (atheroma).
Bronchodilators
Drugs that cause expansion of the lumina of the air passages of the lungs. Used for treatment of asthma and COPD.
Coagulation
Process of clot formation.
Contraindications
Conditions that render the administration of some drug or some particular line of treatment.
Diabetes Mellitus (DM)
Primarily a disorder of carbohydrates, protein, and fat metabolism secondary to insufficient secretion of insulin or insulin resistance.
Diabetes gastroparesis
Form of nerve damage that affects the stomach; food does not move through the stomach in a normal way, resulting in nausea and vomiting, or bloating.
Diabetic peripheral neuropathy
Disorder of the peripheral nervous system, a complication of diabetes.
Diuretics
Drugs that promote the excretion of urine.
Edema
Presence of abnormally large amounts of fluid in the tissues of the body.
Extravasation
Discharge or escape of fluid from a vessel into the surrounding tissue that can cause localized vasoconstriction, resulting in sloughing of tissue and tissue necrosis if not reversed with an antidote.
Gastroesophageal Reflux Disease (GERD)
Inflammation of the lower esophagus from regurgitation of acid gastric contents; symptoms include heartburn.
Hematoma
Localized collection of blood in the tissue resulting from a break in the wall of the blood vessel.
Hyperlipidemia
Elevations of plasma lipid concentration.
Hypertension
Persistently high arterial blood pressure, usually exceeding 140/90 mmHg
Idiosyncratic Reaction
Unusual response that is peculiar to the individual.
Infiltration
Diffusion of fluid into a tissue; often used interchangeably with extravastation.
Metabolic acidosis
Condition resulting from accumulation of acid or depletion of alkaline reserves (bicarbonate in the blood and body tissues).
Opioids
Drugs, natural or synthetic, that have activity similar to that of morphine.
Osteoporosis
Disease of bone that leads to an increased risk for fracture; bone material density (BMD) is reduced, and bone micro architecture is disrupted.
Parenteral
Not through the gastrointestinal tract, but by injection through some other route.
Parkinson’s Disease (PD)
Degenerative neurologic disease of the brain that often impairs motor skills, speech, and other functions.
Peristalsis
Waves of contraction that propel contents through the GI tract.
Pharmacokinetics
Study of the metabolism and action of drugs with particular emphasis on the time required for absorption, duration of action, distribution in body, and method of excretion.
Schizophrenia
Chronic mental disorder characterized by periods of withdrawn or bizarre behavior.
Thromboembolic disorders
Conditions involving the partial or complete obstruction of a blood vessel.
Antianemic agents
Drugs used for treatment of anemia (subnormal concentration of erythrocytes or hemoglobin in blood) may be due to deficiency in in iron, folic acid, or vitamin B12
Anti anxiety agents
Act on CNS to calm or relax patient. Also used in alcohol detoxification, to prevent seizures and other acute withdrawal symptoms.
Antiarrhythmics
Used to treat irregular heartbeats. The agent used to treat depends on if the arrhythmia is in the atria or ventricle.
Antibiotics
Antibiotics or antimicrobials kill or inhibit growth of micro organisms. There are broad-spectrum and narrow-spectrum.
Anticoagulants
Inhibit the clotting of blood or increase the coagulation time used to prevent thromboembolic disorders.
Anticonvulsants
Prevent or control occurrence of seizures. They do not treat the cause of seizures; they reduce or eliminate activity.
Antidepressants
Often take 6-12 weeks to achieve their maximal therapeutic effect.
Antiemetic
Used to prevent and treat nausea and vomiting. More effective in preventing than treating symptoms once they’ve developed.
Antifungal
Substances that destroy or suppress the growth or multiplication of fungi. 2 groups: those that affect skin or mucosa and those that affect the whole body (systemic).
Antihistamines
Used primarily to treat allergic disorders. Also used to treat symptoms of upper respiratory tract infections. They can be either sedating or nonsedating.
Antihyperlipidemic agents
Hyperlipidemia is associated with the development of atherosclerosis, which leads to coronary heart disease (CHD). These agents reduce cholesterol level.
Antihypertensives
Treats hypertension
Antiparkinson agents
Parkinson’s Disease (PD) is characterized by a resting tremor, rigidity, and brachykinesia.
Antiplatelets
Inhibit platelet aggregation, prevention of myocardial infarction (MI), stroke, and transient ischemia attacks (TIAs).
Antipsychotics
Used to treat psychiatric disorders such as schizophrenia, delusional disorders, acute mania, and agitated states.
Antiulcer Agents
Used to treat peptic ulcers, both gastric and duodenal, and Gastroesophageal Reflux Disease (GERD).
Antiviral Agents
Do not destroy their target pathogen; instead they inhibit its development. Used to treat herpes, chicken pox, shingles, influenza, hepatitis, and HIV.
Cholinesterase Inhibitors
Increase levels of acetylcholine, a major neurotransmitter in CNS.
Coagulants
Control hemorrhage or to speed coagulation.
Corticosteroids
Used to reduce the symptoms associated with chronic inflammation disorders or short term treatment.
Hormones
Affect endocrine system.
Laxatives
Promote passage and elimination of fences from large intestine.
Mood-Stabilizing Drugs
Prevent mood swings in patients with manic-depressive (bipolar) disorder.
No steroidal Anti-Inflammatory Drugs (NSAIDs)
Analgesic, antipyretic (fever reducing), and anti-inflammatory actions.
Osteoporosis Drugs
Treat bone loss.
Sedatives or Hypnotics
Can produce varying degrees of CNS depressing ranging from mild sedation to sleep.
Stimulants
Increase activity in brain or spinal cord. Examples: Adderall or Ritalin
Thrombolytics
Dissolve thrombi (clots) that have already formed. Administered parenterally in case of myocardial infarction (MI) or stroke.