Pharmacology and The Dental Patient Flashcards
name some examples of analgesic drugs for pain relief
(non-opioid, corticosteroids, narcotics)
ibuprofen
paracetamol
orabase
codeine
what’s the importance of CYP2D6 variation in coding metabolism
liver metabolises codeine -> morphine
name examples of sedative drugs (pharmacogenetics)
N2O (laughing gas)
Midazolam
what’re the ideas characteristics of short-course antibiotic therapy
- minimise antibiotic exposure
- preserve healthy Microbiota
- effective antigen eradication
what’s the purpose of analgesics
acute pain relief
give some details of Midazolam
- how drug is delivered
- onset
- effects on the body (what does it bind to to achieve this)
- I.V
- rapid onset
- slows b.r & bpm (GABAa)
what are some localised oral lesions that can be treated w. antibiotics (2)
periodontal abscesses
acute necrotising ulcerative gingivitis
what’re some antibiotics that can be used for treatment of orofacial infections (3)
- betalactams
- penicillin
- tetracyclines
how may antidepressants effect dental treatment
xerostomia
- block ACh (reduces mucus & saliva)
how does angina medication effect dental treatment (nitrates)
- vasodilators
how do antihypertensives effect dental treatment
fall in b.p. when standing up (orthostatic hypertension)
vasodilation
autonomic dysfunction
how do opioid analgesics effect dental treatment
codine
therapy for chronic pain
heroin addicts (dental decay)
how do hypoglycaemics effect dental treatment
diabetics
hypoglycaemic episode
effect food intake of patient
how do steroids effect dental treatment
anti-inflammatory
adrenal suppression
side effects from steroid therapy
how do B-blockers effect dental treatment
block sympathetic influences
heightened sensitivity to vasopressors
risk if acute hypertensive episodes
decrease in hepatic blood flow
reduced metabolism of lidocaine
