Pharmacology Flashcards

1
Q

What is the MOA of Donepezil, Galantamine and Rivastigmine?

A

Reversible ACh esterase inhibitor

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2
Q

What are the ADR’s of Donepezil?

A

Abnormal dreams, aggression, agitation, anorexia, diarrhoea, dizziness, fatigue, hallucinations, headache, insomnia

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3
Q

What are the CI’s of Donepezil?

A

Asthma, COPD, cardiac arrythmias

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4
Q

What are the ADR’s of Galantamine?

A

Abdominal pain, bradycardia, reduced appetite, depression, diarrhoea, dizziness

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5
Q

What are the CI’s of Galantamine?

A

GI pathology, cardiac arrhythmias, epileptic, COPD, asthma

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6
Q

What are the ADR’s of Rivastigmine?

A

Abdominal pain, agitation, anorexia, anxiety

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7
Q

What are the CI’s of Rivastigmine?

A

GI disease, COPD, asthma, epileptic

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8
Q

What is the MOA of Memantine?

A

NMDA receptor antagonist + nAChR antagonist

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9
Q

What are the ADR’s of Memantine?

A

Balance disorders, constipation, dizziness, drowsiness, dyspnoea, headache, hypertension

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10
Q

What are the CI’s of Memantine?

A

Epileptic

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