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In service CCM > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

half life of lorazepam?

A

12h

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2
Q

propofol mechanism?

A

GABA agonist

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3
Q

side effects of propofol?

A

apnea, hypertriglyceridemia, PRIS

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4
Q

PRIS signs sx?

proposed mehcanism?

A

refractory bradycardia with one of the following: acidosis, rhabdo, hyperlipidemia, fatty liver
- disorder of mitochondrial metabolism

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5
Q

Dexmedetomidine MOA?
how is excreted?
where does biotransformation take place?

A

alpha2 agonist

  • almost completely excreted in urine
  • liver, so must dose adjust for liver and kidney dysfunction
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In service CCM (17 decks)

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