Pharmacology

Question 1

What is the therapeutic window or range of a drug?

Answer 1

the range of a drug serum concentration associated with a high degree of efficacy and a low risk of undesired dose related adverse reactions

Question 2

What is the therapeutic index of a drug?

Answer 2

the ratio between the toxic dose and therapeutic dose of a drug used as a measure of the relative safety of the drug for a particular treatment. A drug with a narrow therapeuti index may cause toxic results with small changes in dosess

Question 3

What class of drug is atropine?

Answer 3

anticholinergic

Question 4

Why is atropine frequently used before and during surgery in small animals?

Answer 4

to reduce or prevent secretions of the respiratory tract and to reduce bradycardia

Question 5

what kind of drug is guaifenesin?

Answer 5

a neuromuscular blocker

Question 6

For what purpose is guaifenesin commonly used?

Answer 6

it is used in equine and bovine surgery to selectively depress transmission of nerve impulses at the internucial neurons of the spinal cord, brainstem and subcortical regions of the brain.

Question 7

what are the symptoms of neuromuscular blocker overdose?

Answer 7

increased risk for hypotension, histamine release and prolonged muscle blockade