Pharmacology Flashcards
Mechanism of action of lamotrigine and topiramate
Blockage of AMPA receptors, leading to decreased glutamate excitatory effects
*Lamotrigine also blocks sodium channels
Mechanism of action of felbamate
- Blocks NMDA receptors
* Blocks sodium channels
Phenytoin, carbamazepine and valproate block sodium channels in which state
Inactivated state
DOC for trigeminal neuralgia
Carbamazepine
Carbamazepine increases secretion of which hormone
ADH
Mechanism of action of valproate
- Blocks sodium channels
- Inhibits GABA transaminase
- Blocks T-type calcium channels
Mechanism of action of tiagabine
Inhibits GABA reuptake
Triptans are agonists at which serotonin receptors
5HT1d
Prophylactic drugs for cluster headaches
Calcium channel blockers (verapamil)
Type of drugs that increases duration of phase 1 of depolarizing muscle relaxants
AChE inhibitors
Mechanism of action of gabapentin
Inhibits presynaptic voltage-gated calcium channels
Mechanism of action of levetiracetam
Disrupts neurotransmitter vesicle fusion
Drug that can be used for chronic tension headache
Amitriptyline
Types of drugs that promote drainage of aqueous humor
M3 and prostaglandin analogs
Anti-VEGF monoclonal antibody that can be used to treat secondary macular degeneration
Ranibizumab
Drug used in Wilson’s disease for patients who can’t tolerate penicillamine
Trientine
Mechanism of action of brimonidine
Alpha 2 agonist