General principles Flashcards

1
Q

Secondary vesicle from which the retina and the optic nerves are derived

A

Diencephalon

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2
Q

Only cranial nerve that is myelinated

A

Optic nerve

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3
Q

Branches of the vertebral arteries

A
  • Anterior spinal artery

* Posterior inferior cerebellar artery (PICA)

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4
Q

Function of D1 receptors

A

Excitation of direct pathway

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5
Q

Function of D2 receptors

A

Inhibition of indirect pathway

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6
Q

The corticospinal tract traverses through which part of the internal capsule

A

Posterior limb

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7
Q

The ACA irrigates which part of the internal capsule

A

Anterior limb

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8
Q

Describe the Papez circuit

A
  • Mammillary body
  • Thalamus (anterior nucleus)
  • Cingulate gyrus
  • Hippocampus (via fornix is connected again to the mammillary body)
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9
Q

Muscle that elevates posterior tongue during swallowing

A

Palatoglossus

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10
Q

Only muscle of the tongue that is innervated by the CN 10

A

Palatoglossus

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11
Q

Cell of the CNS that acts as an extracellular potassium buffer

A

Astrocyte

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12
Q

Cell of the CNS that derives from the mesodermal layer

A

Microglia

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13
Q

Characteristics of C fibers

A

Slow and unmyelinated

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14
Q

Characteristics of Adelta fibers

A

Fast and myelinated

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15
Q

Substances that can cross the blood-brain barrier via carrier-mediated transport mechanisms

A

Glucose and aminoacids

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16
Q

Parts of the blood-brain barrier that have fenestrated capillaries

A
  • Area postrema (vomiting after chemo)
  • OVLT (organum vasculosum lamina terminalis) - (osmotic sensing)
  • Neurohypophysis
17
Q

Hunger is controlled by which area of the hypothalamu

A

Lateral area

18
Q

Hormones that act on the lateral area of the hypothalamus

A
  • Ghrelin (stimulates)

* Leptin (inhibits)

19
Q

Satiety is controlled by which area of the hypothalamus

A

Ventromedial area

20
Q

Hormone that acts on the ventromedial area of the hypothalamus

A

Leptin (stimulates)

21
Q

Part of the hypothalamus that controls heat dissipation

A

Anterior hypothalamus

22
Q

Part of the hypothalamus that controls heat conservation

A

Posterior hypothalamus

23
Q

Substances that decrease REM sleep

A
  • Alcohol
  • Barbiturates
  • BZD
  • Norepinephrine
24
Q

Sleep changes in the elderly

A
  • Decreased REM
  • Decreased slow-wave sleep
  • Increased sleep latency
  • Increased awakenings
25
Q

The ventral postero-lateral nucleus of the thalamus receives input from which tracts

A
  • Spinothalamic

* Dorsal columns/medial lemniscus

26
Q

The ventral postero-medial nucleus of the thalamus receives input from which tracts

A

Trigeminal and gustatory pathway

27
Q

The lateral geniculate nucleus connects CN 2 to which part of the cortex

A

Calcarine sulcus

28
Q

Deep nuclei of the cerebellum

A

From lateral to medial…

  • Dentate
  • Emboliform
  • Globose
  • Fastigial

(Don’t Eat Greasy Foods)

29
Q

Formula for cerebral perfusion pressure (CPP)

A

CPP = MAP - ICP

30
Q

The middle meningeal artery enters the brain through which cranial foramen

A

Foramen spinosum

31
Q

Function of the nucleus solitarius

A

Visceral sensory information (CN 7, 9, 10)

32
Q

Function of the nucleus ambiguus

A

Motor innervation of the pharynx, larynx, upper esophagus (CN 9, 10, 11)

33
Q

Function of the dorsal motor nucleus

A

Sends autonomic fibers to heart, lung, upper GI

34
Q

Electrolytes that have a higher concentration in CSF than in serum

A

Sodium and magnesium

35
Q

Muscle spindles respond to which type of stimulus

A

Increase in muscle stretch

36
Q

Golgi tendon organs respond to which type of stimulus

A

Increase in muscle force

37
Q

Mechanism of action of tetrodotoxin (puffer fish)

A

Binds to sodium channels, inhibiting sodium influx and preventing action potential conduction

38
Q

Function of Clarke’s nucleus

A

Send unconscious proprioceptive information to the cerebellum

39
Q

Describe vestibular nystagmus

A

Slow eye deviation towards the lesioned site with fast corrective deviation away from the lesioned site