Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Gastrointestinal Kaplan > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Pharmacologic treatment of glucagonoma and somatostatinoma

A
  • Octreotide

* Interferon alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

H2 blockers produce a reversible or irreversible block

A

Reversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

H2 blockers that decrease renal excretion of creatinine

A

Cimetidine and ranitidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Proton pump inhibitors produce a reversible or irreversible block

A

Irreversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Adverse effects of proton pump inhibitors

A
  • Increased risk of C difficile infection
  • Pneumonia
  • Decrease in serum Mg (long-term)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Decrease in which electrolyte is a common side effect of all antacids

A

Potassium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Most important side effects of aluminum hydroxide

A
  • Constipation

* Hypophosphatemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mechanism of action of misoprostol

A

PGE1 analog

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Reversible oligospermia is a side effect of which gastrointestinal drug

A

Sulfasalazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Mechanism of action of loperamide

A

Agonist at mu receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Only serotonin receptor that is not G-coupled

A

HT3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

DOC in vomiting caused by gastrointestinal irritation

A

Ondansetron (there is increased serotonin secretion in these states)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DOC for migraine vomiting

A

Metoclopramide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Mechanism of action of senna

A

Enteric nerve stimulation, leading to colonic contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Etiologic agent of melanosis coli

A

Senna

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Mechanism of action of aprepitant

A

Substance P antagonist that block NK1 receptors in the brain

17
Q

Clinical use of aprepitant

A

Chemotherapy-induced nausea and vomiting

18
Q

CNS area that is affected by metoclopramide and ondansetron

A

Area postrema in the medulla (chemoreceptor trigger zone)

19
Q

Mechanism through which metoclopramide promotes motility

A

Increase in the sensitivity to acetylcholine

20
Q

Docusate belongs to which types of laxatives

A

Stool softener

21
Q

Examples of irritant laxatives

A
  • Castor oil
  • Senna
  • Bisacodyl
22
Q

Mechanism of action of irritant laxatives

A

Decrease water reabsorption and stimulate secretion

23
Q

Examples of lubricating laxatives

A
  • Mineral oil

* Glycerin

24
Q

Mechanism of action of ursodiol/ursodeoxycholic acid

A

Concentrates in bile and decreases biliary cholesterol by suppresing by suppressing hepatic synthesis and secretion of cholesterol as well as inhibiting its intestinal absorption, leading to partial solubilization of cholesterol from gallstones

25
Q

First-line chelating agent used in arsenic poisoning

A

Dimercaprol

26
Q

Reason for which opioid analgesics are contraindicated in hypotensive patients

A

They stimulate the release of histamine, leading to vasodilation of blood vessels and itching

Gastrointestinal Kaplan (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions