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MS4 - Anaesthetics > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Side effects of accidental arterial propofol administration

A

Hyperaemia

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2
Q

Side effects of accidental arterial Atracurium administration

A

Ischaemia

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3
Q

Side effects of accidental arterial Ketamine administration

A

Necrosis

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4
Q

Side effects of accidental arterial Phenytoin/Thiopental administration

A

Ischaemia
Necrosis
Death

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5
Q

Seldinger technique

A

Passing tube over guide wire

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6
Q

Peak effect time after administration of morphine

A

10-15 mins

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7
Q

Fentanyl

A

Synthetic opiod
Rapid onset
Short duration

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8
Q

Diclofenac

A

NSAID
Used post operatively
IV dose 75 mg

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9
Q

NSAID side effects

A

Bleeding
Renal impairment
Peptic ulcers

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10
Q

Paracetamol dose

A

> 50 kgs 1 g QDS

< 50 kgs 15 mg/kg QDS

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11
Q

Ondansetron

A

Antiemetic
5HT3 antagonist
4 mg IV

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12
Q

Cyclizine

A

Antiemetic
H1 antagonist
50 mg IV

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13
Q

Cyclizine side effects

A

Anticholinergic side effects
Tachyarrhythmias

Must be given by slow IV injection

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14
Q

Prochlorperazine

A

Antiemetic
Dopamine (D2) antagonist
12.5 mg IM

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15
Q

Metoclopramide

A

Antiemetic
Dopamine (D2) antagonist
Slow onset

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16
Q

Dexamethasone

A

Antiemetic
Slow onset, long half life
4-8 mg

17
Q

Iontropes examples

A

adrenaline
dobutamine
dopexamine

18
Q

Vasopressor eg

A

NA

19
Q

Normal V/Q ratio

A

0.95

20
Q

Effect of increasing first pass metabolism

A

drugs get removed faster

21
Q

First pass metabolism enzyme

A

P450

22
Q

Abx inducing P450

A

rifampicin

23
Q

Abx inhibiting P450

A

clarithromycin

MS4 - Anaesthetics (7 decks)

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