Pharmacology

Question 1

What is the characteristic side effect of amoxicillin?

Answer 1

Rash following mononucleiosis

Question 2

What is the characteristic side effect of erythromycin?

Answer 2

GI upset

Long QT

Question 3

What is the characteristic side effect of metronidazole?

Answer 3

Reaction with alcohol

Question 4

What is the characteristic side effect of doxycycline?

Answer 4

Photosensitivity

Question 5

What is the characteristic side effect of flucloxacillin and co-amoxiclav?

Answer 5

Cholestasis

Question 6

Name some CYP inducers

Answer 6

If you drive your CAR up the RAMP through the BARBed wire into St. John’s woods, you will be chronically attacked by an oPHENder.

Carbamazepine
Rifampicin
Barbiturates
St. John's wort
Chronic alcohol
Phenytoin

Question 7

Name some CYP inhibitors

Answer 7

Big MAC acutely drinks alcohol with grapefruit juice and ICE - then he needs cimetidine for Stomach Ache.

Macrolides
Acute alcohol - binging
Grapefruit juice
Isoniazid
Cimetidine
Sulphonamides
Amiodarone

Question 8

What drug monitoring is required for methotrexate?

Answer 8

FBC
U&E
LFT

Baseline, weekly till stable then every 2 months

Question 9

What drug monitoring is required for statins?

Answer 9

LFTs

Baseline, 3 months, 12 months

Question 10

What drug monitoring is required for amiodarone?

Answer 10

Thyroid function
LFT
CXR

Baseline. Then TFT and LFT 6 monthly

Question 11

What drug monitoring is required for lithium?

Answer 11

Thyroid function
U&E
Baseline then every 6 months

Lithium levels weekly then 3 months