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Principles > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Sympathetic pre-ganglionic neurotransmitter

A

ACh

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2
Q

Sympathetic post-ganglionic neurotransmitter

A

NA

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3
Q

Site of sympathetic outflow from the spinal cord

A

Thoraco-lumbar

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4
Q

Preganglionic neurones have … axons than postganglionic neurones

A

shorter

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5
Q

Parasympathetic pre-ganglionic neurotransmitter

A

ACh

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6
Q

Parasympathetic post-ganglionic neurotransmitter

A

ACh

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7
Q

Parasympathetic outflow from spinal cord

A

cranio-sacral

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8
Q

Sympathetic effects on the heart

A

increases HR, increases force of contraction

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9
Q

Sympathetic effects on the lungs

A

relaxes bronchi, reduces mucus production

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10
Q

Sympathetic effects on the GI tract

A

reduces motility and constricts sphincters

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11
Q

Sympathetic effects on the vasculature

A

constricts mostly, but relaxes in skeletal muscle

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12
Q

Sympathetic effects on the adrenal gland

A

release of adrenaline

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13
Q

Sympathetic effects on the penis

A

ejaculation

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14
Q

Parasympathetic effects on the heart

A

slows HR

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15
Q

Parasympathetic effects on the lungs

A

constricts bronchi and increases mucus

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16
Q

Parasympathetic effects on the GI tract

A

increases motility and relaxes sphincters

17
Q

Parasympathetic effects on the vasculature

A

no effect

18
Q

Parasympathetic effects on the adrenal glands

A

no effect

19
Q

Parasympathetic effects on the penis

A

erection

20
Q

Overview of neurotransmission (9points)

A
  1. Uptake of precursor
  2. Synthesis of transmitter
  3. Storage of transmitter in vesicle
  4. Causes depolarisation of AP
  5. Results in Ca2+ influx through voltage gated ion channels
  6. Calcium induced exocytosis of transmitter out of presynaptic ganglion
  7. Activation of G-proteins or ligand gated ion channels
  8. Reuptake of transmitter or
  9. Enzyme-mediated inactivation

Principles (4 decks)

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