*Pharmacology 4 (lecture 4) - only partially finished Flashcards
What drugs can be used to treat hypertension? (6)
Alpha blockers ACEI ARB Beta blockers Calcium channel antagonists Thiazide like diuretic
What do all beta blockers end in?
-olol
What do ACEI end in?
-pril
What do all ARB end in?
-artan
What drugs can be used to treat angina? (6)
Beta blockers Calcium antagonists Nitrates Nicorandil Ivabradine Ranolazine
What are the 3 categories of anti-thrombotic drugs?
Anti-Platelet drugs
Anti-coagulants
Fibrinolytics
What are 4 examples of anti-platlet drugs?
Aspirin
Clopidogrel
Prasugrel
Ticagrelor
What are 3 examples of anti-coagulant drugs?
Warfarin
Rivaroxaban
Dabigatran
What are 2 examples of fibrinolytic drugs?
Streptokinase
Tissue Plasminogen activator (tPA)
What are 2 groups of anti-cholesterol drugs?
Statins
Fibrates
What are the 5 main groups of CV drugs?
Anti-hypertensives Anti-anginals Anti-thrombotic Anti-cholesterol Anti-arrhythmics (+others)
How do diuretics work?
They block Na reabsorption in the kidneys and reduce the amount of fluid in the body
What are the 2 categories of diuretics?
Thiazide like diuretics (mild) Loop diuretics (stronger)
Example of a thiazide like diuretic?
Used to treat?
Bendrofluazide
Hypertension
Example of a loop diuretic?
Used to treat?
Furosemide
Heart failure
Side effects of diuretics? (4)
Hypokalaemia (tired, arrhythmias)
Hyperglycaemia
Increased uric acid = gout
Impotence
How do beta blockers work?
They block beta 1 +/- beta 2 adrenoceptors
What is an example of a cardioselective beta blocker?
What is this used to treat? (3)
Atenolol
Angina
Hypertension
Heart failure
What is an example of a non selective beta blocker?
What is it used to treat?
Propranolol
Thyrotoxicosis
Contra-indication for use of beta blocker?
Asthma
Side effects of beta blockers?
Asthma
Tiredness
Heart failure (good in the long term but can worsen it in the short term)
Cold peripheries
2 types of calcium antagonists?
Dihydropyridines
Rate limiting calcium antagonists
Example of a dihydropyridine?
What is used to treat? (2)
Side effects?
Amlodipine
Hypertension and angina
Ankle oedema
2 examples of rate limiting calcium antagonists?
What are they used to treat?
What should these never be used with?
Verapamil, Dilitiazem
Hypertension, angina, SV arrhythmias
Beta blockers
How do alpha blockers work?
Block alpha adrenoceptos to cause vasodialtion
What are alpha blockers used to treat?
hypertension
Prostatic hypertrophy
Example of alpha blocker?
Side effects?
Doxazosin
Postural hypotension
How do ACEI work?
Block angiotensin I from becoming angiotensin II
Example of an ACEI?
Lisinopril
What are ACEI used for?
Hypertension and heart failure
In terms of the kidneys what is ACEI good and bad for?
Good for diabetic nephropathy
Bad for renal artery stenosis
