Pharmacology 2 Flashcards
When drug activity is at the site of administration
Local effect
When a drug is introduced into the venous (circulatory) system and carried to the site of activity
Systemic effect
The breaking apart of a tablet into smaller pieces
Disintegration
When smaller pieces of a disintegrated tablet dissolve in solution
Dissolution
The pH scale measures the acidity or the opposite (alkalinity) of a substance. 7 is neutral on the scale, values below which represent increasing acidity, and above which represent increasing alkalinity.
pH
a clear, not necessarily colorless, liquid made up of one or more ingredients dissolved in a solvent.
Solution
A liquid that can dissolve another substance to form a solution.
Solvent
Water based and most common kind of oral solution
Aqueous solutions
Solutions that predominately contain solvents other than water, either alone or in addition to water. Ex: glycerin, alcohol, and propylene glycol can be used in oral solutions
Nonaqueous solutions
Concentrated or nearly saturated solutions of sucrose in water. More viscous (thicker) than water, and contain less than 10% alcohol.
Syrups
Clear, sweetened, hydroalcoholic liquids intended for oral use. Its alcohol ranges from 5-40% (10-80 proof)
Elixirs
Alcoholic or hydroalcoholic solutions of nonvolatile substances. Its potent drugs have 10g of the drug in each 100ml.
Tinctures
Formulations in which the drug does not completely dissolve in the solvent.
Suspensions
A stabilising agent in emulsions
Emulsifer
Under the tongue
Sublingual
Painful swollen veins in the anal/rectal area, generally caused by strained bowel movements from hard stools.
Hemorrhoid
Ingredients in a formulation designed to control the pH
Buffer system
Sterile condition is one which is free of all microorganisms, both harmful and harmless.
Sterile
Administrated directly into veins
Intravenous injections
Administrated into muscle tissue and generally result in a slower onset but longer duration of action compared to IV administration.
Intramuscular injections
Administered into the subcutaneous tissue of the skin.
Subcutaneous injection
Administered into the top layer of the skin at a slight angle using short needles
Intradermal injections