Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MSRA > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

PPI mechanism?

A

blockade of the H+/K+ ATPase on the gastric parietal cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Side effects of PPI

A

Hyponatraemia
Hypomagnesia
Increased risk of fractures with long term use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Oral to subcut morphine conversion?

A

divide by 2
ie - 10mg oramorph QDS = 5mg S/C morphine QDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How is breakthrough morphine dose calculated?

A

1/6 of total daily morphine dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

codeine to morphine conversion (both oral)?

A

divide by 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

tramadol to morphine (oral) conversion?

A

divide by 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

oral morphine to oral Oxy conversion?

A

divide by 1.5-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Benzo mechanism?

A

enhance the effect of GABA (inhibitory neurotransmitter)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

max time benzos should be prescribed for?

A

2-4 weeks (risk of tolerance and dependence)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how to wean benzos?

A

convert to equivalent dose of diazepam (longer lasting) and reduced dose by 1/8 every 2 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

side effects of SSRIs?

A

increased anxiety/low mood to start with - can have increased suicidal ideation
hyponatraemia
GI symptoms
Citalopram can prolong QT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

common interactions with SSRIs?

A

NSAIDs (increased GI bleed risk)
Warfarin
Aspirin
Triptans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

mechanism of typical antipsychotics?

A

D2 receptor antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

mechanism of atypical antipsychotics?

A

D2/D3/D4/5-HT receptor antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

examples of typical antipsychotics?

A

haloperidol
chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

examples of atypical antipsychotics?

A

risperidone
olanzapine
clozapine

17
Q

examples of extra-pyramidal side effects

A

acute dystonia (inc. torticolis and oculogyric crisis)
akithesia
tardive dyskinesia
parkinsonism

18
Q

how is acute dystonia managed?

A

procyclidine

19
Q

other side effects of antipsychotics?

A

extra-pyramidal side effects
anti-muscarinic
sedation
weight gain
long QT
raised prolactin
impaired glucose tolerance
neuroleptic malignant syndrome

20
Q

examples of quinolone abx?

A

ciprofloxacin
levofloxacin

21
Q

side effects of quinolones?

A

tendonitis/rupture (esp achilles)
QT prolongation
reduced seizure threshold in epilepsy
cartilage damage in kids

22
Q

when should quinolones be avoided>

A

pregnancy/breastfeeding
G6PD deficiency

MSRA (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions