Pharmacology

Question 1

Parasympathetic

Answer 1

Acetylcholine (miosis)

Question 2

Sympathetic

Answer 2

Noradrenaline (mydriasis)

Question 3

Full agonist

Answer 3

Drugs that and bind and fully activate receptor sites

Question 4

Partial agonists

Answer 4

Drugs that bind to the receptor sites but have lower efficiency than full agonists

Question 5

Antagonist

Answer 5

Prevent the neurotransmitter from activating the site

Question 6

Topical drugs

Answer 6

Applied or absorbed through skin/mucus membrane

Question 7

Chloramphenicol

Answer 7

P license
Acute bacterial conjunctivitis only
5 days
10ml 0.5% drops
4gms 1% ointment
Hazardous waste

Question 8

Tropicamide Hydrochloride

Answer 8

Antimuscarinic antagonist
0.5% and 1%
POM medicine
Non-hazardous waste
Unwanted effect on accommodation
20mins to take effect
Lasts 8-9 hours

Question 9

Phenylephine Hydrochloride

Answer 9

Used if HES recommends/ if cannot dilate enough
2.5% and 10%
P medicine
Cardiovascular reactions
Lasts 5-7 hours

Question 10

Cyclopentolate Hydrochloride

Answer 10

1% or 0.5%
POM
Reduced accommodation for 7-8hours
Mydriasis for 24-36hours
Stings on insert

Question 11

Fluroscein

Answer 11

Colours tear film
P medicine
Assesses corneal integrity, CL fitting, TBUT
Impregnated strips

Question 12

OADR

Answer 12

Aspirin; subconjunctival haemorrhage
Steroids; cataracts, increase IOP
Hydroxychloroquine; retinopathy, keratopathy
Tamoxifen; mydriasis, reduced accommodation
Piriton; blurred vision, mydriasis