Pharmacology Flashcards

1
Q

A positive inotrope drug that can be given with quinidine to help convert horses with artial fibrillation.

A

Digoxin

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2
Q

Most common side effect of digoxin when giving this medication

A

higher blood concentration

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3
Q

What drug is typically reserved for bacteria that is strictly susceptible to this medication because of the side effects that can be produced in the human administering the drug.

A

Chloraamphenicol

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4
Q

Side effects of chloramphenicol include?

A

Disrupting the mitocondrial function in bone marrow cells of humans and causing aplastic anemia

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5
Q

What is the aminoglycoside that can be given IV to horses

A

Genticyn

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6
Q

What is the aminoglycoside that is generally injected into the joints of horses?

A

Amilgyde-V

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7
Q

What is a class known to be ototoxic and nephrotoxic

A

Aminolgycosides

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8
Q

Which drug is the only narcotic used routinely in horses and is considered the strongest analgesic that can be given to them.

A

Torbugesic (butorphanol)

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9
Q

How long can Torbugestic (butorphanol) have an analgesic effect

A

up to 4 hours

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10
Q

Which drug is prohibited in performance horses during competition?

A

Torbugesic (butorphanol)

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11
Q

What 2 frugs are the lipolytic tetracyclines that can be readily absorbed through the GI tract?

A

Doxycycline and minocyline

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12
Q

What supplement can be given to horses with an insulin resistant endocrine disorder?

A

Metforin

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13
Q

The efficacy of metforin is not great as it is not absorbed through what?

A

The intestinal tract

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14
Q

What drug is the ocular antifungal that can be used to treat fungal infections and fungal ulcers in horses

A

Fluconazole

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15
Q

Which drug treats fungal infections and fungal ulcers in horses?

A

Flucanazole

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16
Q

What does Levothyroxine treat in horses?

A

Hypothryroidism

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17
Q

What medication treats hyperthyroidism?

A

Levothyroxine

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18
Q

What formulation does Levothyroxine normally come in that can be mixed with food?

A

powdered

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19
Q

What NSAID comes as a topical paste that can be applied directly onto the distal limbs for lameness issues?

A

Surpass (diclofenac sodium)

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20
Q

How is a portion of surpass (diclofenac sodium) absorbed

A

systemically

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21
Q

What drug is the only fluroquinolone used in horses?

A

Baytril (enrofloxacin)

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22
Q

This medication is rarely used but works by distributing the bacterias DNA function

A

Baytril (enrofloxcin)

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23
Q

How long do short acting glucocorticoids last for in the body?

A

12 hours

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24
Q

How long do intermediate acting steroids last for in the body?

A

12-36 hours

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25
How long do long acting steroids last for in the body?
48 hours and longer
26
Which drug is an antiulcer medication that forms a paste and binds to ulcer sites once mixed with stomach acid?
Carafate
27
What compound can be used to help reduce swelling caused by trauma?
DSMO (dimethyl sulfoxide)
28
How can DSMO (dimethyl sulfoxide) be given?
topically or IV
29
The only from of penicillin G that can be administered IV is the aqueous solution which has to be mixed with either of these 2 elements.
Sodium and potassium
30
Which drug is that cardiac medication that is used to treat artial fibrillation in horses?
Quinidine
31
Which drug can have serious side effects and is generally given by _______ administration
quinidine and oral
32
What is the most common steroid group used in horses?
Glucocorticoids
33
What are glucocorticoids most commonly used for?
Anti-inflammitory effects
34
What is a proton pump inhibitor that can be used to treat GI ulcers
Gastro-guard (omeprazole)
35
What binds to parietal cells and inhibits the movement of hydrogen ions into the stomach?
Gastro-gaurd (omeprazole)
36
What is the anti-inflammatory eye medication that can be used to relieve pain and swelling associated with ocular disordes
Diclofenac ophthalmic
37
Penicillin is a batericidal antimicrobial that is more effective against which gram bacteria.
positive
38
This medication attacks the bacterial enzymes so it can only be used for actively dividing bacterial colonies.
Penicillin
39
What drug is the NSAID that was released in 2012 and can be used to control pain associated with osteoarthritis
Equioxx (Fibcoxib)
40
What drug can be used for both muculoskeletal pain relief as well as _______ pain which can be associated with colic
Banamine (fluxin meglumine) and visceral
41
Potentiated sulfonamides can have serious side effects like?
Thrombocytopenia, leukopenia, anemia
42
Should potentiated sulfonamides be used for a prolonged period of time?
No, due to its side effects
43
What should be given to a horse suffering from endotoxemia because it inhibits prostanoid produciton
Banamine
44
What is the only cephalosporin used in equine medicine
Naxcel (ceftiofur)
45
What drug is given to mares to terminate a pregnancy?
LUTALYSE (dinoprost thromethmine)
46
Which is the GI antibiotic that can be given to clear the GI tract of protozoa that are causing disease.
Flagyl (metronidazole)
47
What drug is known to cause some transient neurologic side effects in horses?
Flagyl (metronidazole)
48
What is an emollient laxative that can be given to horses that have inpactions?
mineral oil
49
What should not be given to horses that may undergo surgery?
Mineral oil
50
What do NSAIDS block?
Prostaglandin production
51
What does Cox-1 help protect?
the stomach
52
Cox-2 are prostaglandins that are produced in response to what?
Pain
53
Acepromazine is a _________ tranquilizer that can be used as a sedative in horses.
phenothiazine
54
Which medication must be given before the animal becomes overly excited
Acepromazine
55
This medication should be used with extreme caution in stallions as it can cause permanent paralysis of the retractor penis muscle
Acepromazine
56
A dopamine antagonist that allows for prolactin secretion
EQUIDONE (domperidone)
57
EQUIDONE (domperidone) can be used in what?
fescue toxicosis, stimulation of lactation in agalactic mare, and can be used to induce lactation in nurse mares
58
If EQUIDONE (domperidone) is used for ______, it should be stared _____ days prior to the expected due date and continue ______ days after surgery
fescue toxicosis, 10-15, 5-10
59
An indigestible plant fiber that can be used as a bulk laxative as it osmotically pulls water into the bowel lumen.
Metamucil (psyllium fiber)
60
Metamucil (psyllium fiber) can be useful when treat what kind of colic?
sand
61
What can be used in horses to help with laminitis and colic pain?
Lidocaine
62
Lidocaine blocks pain signals at _____
Level of the spinal cord
63
Toxicity of this drug can lead to severe neurologic signs
Lidocaine
64
An alpha 2 agonist which is classified as a sedative-analgesic.
Dormosedan
65
What can dormosedan be used for?
sedation, or used as an analgesic for viceral pain (especially in colicky horses)
66
This analgesic effects lasts for roughly 45 minutes
Dormosedan
67
The anti-ulcer medication that cannot be given at the same time as other oral medications as it can prevent/disrupt the absorption of other medicaions
Carafate (sucrlfate)
68
Atropine sulfate preparations are used to reduce pain in the eye by doing what to the blood vessels?
dilating
69
Repeated doses of atropine sulfate should be avoided as what could occur?
ulcers
70
Rompun is an ______ __ _______ that can be used for short periods of time (generally only lasts 15-20 mins)
alpha-2 agonist
71
In cases of an overdose what drug can be used to reverse Rompun?
yobine (yohimbine)
72
What is the drug of choice to treat potomac horse fever and leptospirosis?
Doxycycline
73
Which version of doxycycline should be given due to the other causing arrhythmias, collapse, and sudden death even at low doses 1. Oral 2. Injectable
Oral
74
A progestin that can be used to delay estrus in mares, or be used to maintain pregnancy in mares prone to abortion
Regu-mate altrenogest