Pharmacology Flashcards
Pharmokinetics
What the body does to the drug
Pharmacodynamics
What the drug does to the body
Codeine is contraindicated in what patients?
Children under 12
What metabolises codeine to morphine?
- what’s the significance?
CYP2D6
There is a lot of variability between levels in children. Therefore some children rapidly metabolise codeine to morphine leading to overdose!
Gentamicin is toxic where?
Nephrotoxic and ototoxic
Side effects of steroids:
Osteoporosis
Infections - immunosuppresion
Cushing’s symptoms (weight gain, thin skin, diabetes).
Hyperglycaemia
LEUKOCYTOSIS
Psychosis
Can lead to Addison’s
BITCH side effects of amiodarone
Bradycardia
Interstitial lung fibrosis
Thyroid (hyper/o)
Corneal deposits/cutaneous photosensitivity
Hepatitis,HypoTN
Cholestasis with what abx?
Co-amoxiclav is a well recognised cause of cholestasis