Pharmacology Flashcards

1
Q

Pharmokinetics

A

What the body does to the drug

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2
Q

Pharmacodynamics

A

What the drug does to the body

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3
Q

Codeine is contraindicated in what patients?

A

Children under 12

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4
Q

What metabolises codeine to morphine?
- what’s the significance?

A

CYP2D6

There is a lot of variability between levels in children. Therefore some children rapidly metabolise codeine to morphine leading to overdose!

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5
Q

Gentamicin is toxic where?

A

Nephrotoxic and ototoxic

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6
Q

Side effects of steroids:

A

Osteoporosis
Infections - immunosuppresion
Cushing’s symptoms (weight gain, thin skin, diabetes).
Hyperglycaemia
LEUKOCYTOSIS
Psychosis
Can lead to Addison’s

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7
Q

BITCH side effects of amiodarone

A

Bradycardia
Interstitial lung fibrosis
Thyroid (hyper/o)
Corneal deposits/cutaneous photosensitivity
Hepatitis,HypoTN

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8
Q

Cholestasis with what abx?

A

Co-amoxiclav is a well recognised cause of cholestasis

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