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ANESTHESIA SEPT RITES EXAM > Pharmacology 1 > Flashcards

Pharmacology 1 Flashcards

1
Q

What is pharmacodynamics?

A

The study of the biochemical and physiological effects of drugs and their mechanisms of action.

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2
Q

True or False: Pharmacodynamics focuses on the concentration of drugs in the body.

A

False

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3
Q

What is the primary goal of pharmacodynamics in anesthesia?

A

To achieve the desired clinical effect while minimizing adverse effects.

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4
Q

What is the term used to describe the relationship between drug concentration and pharmacologic response?

A

Dose-response relationship

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5
Q

What is the term for the minimum concentration of drug needed to produce a measurable effect?

A

Minimum effective concentration (MEC)

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6
Q

What is the term for the concentration at which additional increases in drug concentration do not produce further pharmacologic response?

A

Ceiling effect

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7
Q

What is the term for the time required for the drug concentration to decrease by half?

A

Half-life

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8
Q

What is the term for the maximum effect that a drug can produce, regardless of the dose?

A

Efficacy

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9
Q

True or False: The potency of a drug is related to its efficacy.

A

False

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10
Q

What is the term for the dose of a drug that produces a specified effect in 50% of the population?

A

Median effective dose (ED50)

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11
Q

What is the term for the dose of a drug that is lethal in 50% of the population?

A

Median lethal dose (LD50)

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12
Q

What is the term for the ratio of the median lethal dose to the median effective dose?

A

Therapeutic index

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13
Q

True or False: A higher therapeutic index indicates a safer drug.

A

True

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14
Q

What is the term for the relationship between drug concentration and the time course of drug effects?

A

Pharmacokinetics

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15
Q

What is the term for the process by which drugs are absorbed, distributed, metabolized, and excreted by the body?

A

Pharmacokinetics

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16
Q

What is the term for the concentration at which a drug produces half of its maximal effect?

A

Potency

17
Q

True or False: Drugs with a higher potency have a higher ceiling effect.

A

False

18
Q

What is the term for the study of the interactions between drugs and their targets of action?

A

Pharmacodynamics

19
Q

What is the term for the time required for the drug to reach the site of action?

A

Onset time

20
Q

What is the term for the time required for the drug to produce its maximal effect?

A

Peak effect time

21
Q

True or False: The duration of drug action is the same as the half-life of the drug.

A

False

22
Q

What is the term for the duration of the drug’s clinical effect?

A

Duration of action

23
Q

What is the term for the process by which a drug is eliminated from the body?

A

Elimination

24
Q

True or False: The volume of distribution is a measure of how extensively a drug is distributed in the body.

A

True

ANESTHESIA SEPT RITES EXAM (10 decks)

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