Pharmacokinetics- Excretion Flashcards
1
Q
What are the routes of excretion?
A
- Kidneys
- Lungs
- GIT
- Breast milk, sweat, tears, saliva
2
Q
How does renal excretion work?
A
Some drugs are reabsorbed
Other drugs are filtered and excreted
3
Q
Glomerular filtration
A
Filters drugs up to 20kda- free drugs only
Dependant on renal blood flow
Declines with age and renal impairment
Glomerular filtration rate (GFR) important for dosing