Pharmacokinetics- Excretion Flashcards

1
Q

What are the routes of excretion?

A
  • Kidneys
  • Lungs
  • GIT
  • Breast milk, sweat, tears, saliva
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2
Q

How does renal excretion work?

A

Some drugs are reabsorbed

Other drugs are filtered and excreted

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3
Q

Glomerular filtration

A

Filters drugs up to 20kda- free drugs only
Dependant on renal blood flow
Declines with age and renal impairment
Glomerular filtration rate (GFR) important for dosing

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