Pharmacokinetics Flashcards
What is pharmacokinetics?
The time course of a movement of a drug into, around and out of the body
What is pharmacokinetics the study of?
Absorption
Distribution
Metabolism (out of body)
Excretion (out of body)
If a drug was to have an effect on the body what does it have to be?
Right place
Right time
For the right amount of time
What does pharmacokinetics data about a drug tell us?
What does to give
How often
How to change the dose in certain medical condition
How some drug interaction occur
What are the 3 factors influencing pharmacokinetics
physico-chemical properties of drugs (drug factors)
Physiological factors
Patient-specific factors
Example of physio-chemical factor
size
solubility in h20
solubility in lipids
Example of physiological factor
nature of barriers
rate of removal
Examples of patient specific factors
age
size/weight
gender
