Pharmacogenomics Flashcards
1
Q
Carbamazepine- test for which gene?
A
HLA-B 1502 (5-10% chance of SJS if +)
2
Q
What gene increases statin myopathy?
A
SLCO1B1 Polymorphism
3
Q
What gene prevents treatment with Abacavir?
A
HLA-B 5701
4
Q
What gene must be + in order to use Maraviroc
A
CCR5 +
5
Q
Clopidogrel is converted to active form by which enzyme?
A
2C19
