Pharmacodynamics

Question 1

describe the difference between orthosteric and allosteric

Answer 1

Orthosteric describes a drug that competes for the same binding site as others, whereas allosteric attaches to a different region on the receptor and still influences.

Question 2

define the term Pharmacodynamics

Answer 2

Drug-cell interaction

Question 3

Define Agonist

Answer 3

Any drug that binds to a receptor and activates that receptor. (causes an action)

Question 4

Define Potency

Answer 4

Potency refers to the concentration of a drug necessary to produce a given response

Question 5

Define Antagonist

Answer 5

A drug that binds to that receptor and prevents activation of that receptor

Question 6

Define De-Sensitization

Answer 6

A term referred to the biological response expected from an administered drug is diminished after repeated prescription.

Question 7

What is Efficacy in terms of pharmacodynamics?

Answer 7

The ability to produce a maximal response regardless of dosage or concentration

Question 8

A patient is experiencing Tachyphalaxis; what does this mean ?

Answer 8

they are becoming desensitized to a prescribed drug very rapidly and experiencing little to no effect.

Question 9

Name 2 receptor super-families

Answer 9

G-Protein Linked receptors ; Ligand gated Ion Channels